NOAEL Data REACH Registered Cosmetic Ingredient

(2-Hydroxyethyl)ethylenediaminetriacetic acid

Also known as: BRN 1804795, N-(Carboxymethyl)-N'-(2-hydroxyethyl)-N,N'-ethylenediglycine, Caswell No. 487B, EINECS 205-759-3, EPA Pesticide Chemical Code 039108 (+8 more)

CAS 150-39-0

(2-Hydroxyethyl)ethylenediaminetriacetic acid (CAS 150-39-0) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for HEDTA →

Cross-Vertical Regulatory Divergence

(2-Hydroxyethyl)ethylenediaminetriacetic acid is classified GHS Danger (H302, H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.

SOURCE Cross-vertical comparison Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 19 fields

Name

(2-Hydroxyethyl)ethylenediaminetriacetic acid

CAS Number

150-39-0

DTXSID

DTXSID1059737

Molecular Formula

C10H18N2O7

InChI Key

URDCARMUOSMFFI-UHFFFAOYSA-N

Monoisotopic Mass

278.111401

Synonyms

BRN 1804795N-(Carboxymethyl)-N'-(2-hydroxyethyl)-N,N'-ethylenediglycineCaswell No. 487BEINECS 205-759-3EPA Pesticide Chemical Code 039108Hamp-ol acid2-Hydroxyethylenediamine triacetateN-Hydroxyethylenediaminetriacetic acidN-Hydroxy-N,N',N'-ethylenediaminetriacetic acid trisodium saltn-Hydroxyethylethylenediamine-n,n',n'-triacetic acidN-(beta-Hydroxyethylethylenediamine)-N,N',N'-triacetic acid(N-Hydroxyethylethylenedinitrilo)triacetic acid

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 5 records

AbsorbentChelating agentViscosity modifierOpaciferFiller

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 6 of 6 studies

Value	Unit	Endpoint	Route	Species	Source
=10	mg/m3	DNEL local	inhalation	Human	ToxValDB_GESTIS_DNEL
=88	mg/m3	DNEL systemic	inhalation	Human	ToxValDB_GESTIS_DNEL
R79J91U341	UNII	FDA UNII substance identifier	-	-	openFDA substances
R79J91U341	UNII	FDA UNII substance identifier	-	-	openFDA substances
R79J91U341	UNII	FDA UNII substance identifier	-	-	openFDA substances
=30	mg/m3	LOAEC	inhalation	Rat	ToxValDB_ECHA_IUCLID

Showing 6 of 6 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records

Status	Name	EC Number	Link
Registered	N-(2-hydroxyethyl)ethylenediaminetriacetic acid	205-759-3	ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL1620428

ChEMBL Phase

Not listed

Adverse Events

Bioactivity

View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for (2-Hydroxyethyl)ethylenediaminetriacetic acid?

(2-Hydroxyethyl)ethylenediaminetriacetic acid has 6 NOAEL studies in the database. The lowest reported value is 10 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

Is (2-Hydroxyethyl)ethylenediaminetriacetic acid used in cosmetics?

Yes, (2-Hydroxyethyl)ethylenediaminetriacetic acid is also indexed as a cosmetic ingredient under the name HEDTA. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for (2-Hydroxyethyl)ethylenediaminetriacetic acid come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Does (2-Hydroxyethyl)ethylenediaminetriacetic acid have different safety status in cosmetics vs industrial chemicals?

(2-Hydroxyethyl)ethylenediaminetriacetic acid is classified GHS Danger (H302, H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.

Is (2-Hydroxyethyl)ethylenediaminetriacetic acid used outside industrial chemicals?

(2-Hydroxyethyl)ethylenediaminetriacetic acid also appears in cosmetics, pharmaceutical databases.