NOAEL Data REACH Registered Cosmetic Ingredient

Phantolide

Also known as: EINECS 239-360-0, UNII-3KM1212J0Y

CAS 15323-35-0

Phantolide (CAS 15323-35-0) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Tetrahydro-hexamethyl-as-indacen-3-one (Phantolide®) →

SOURCE noael studies public
NOAEL studies
8
SOURCE chemical inventory jurisdictions
Regulatory lists
2
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 8 fields
Name
Phantolide
CAS Number
15323-35-0
DTXSID
DTXSID9051743
Molecular Formula
C17H24O
InChI Key
VDBHOHJWUDKDRW-UHFFFAOYSA-N
Monoisotopic Mass
244.182715
Synonyms
EINECS 239-360-0UNII-3KM1212J0Y

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 10 records
DeodorizerFragrance

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 2 records
ListKeywordSource
IFRA TransparencyIFRAIFRA
Europe; Personal care; restrictedEuropean CommissionCosIng

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 8 of 8 studies
ValueUnitEndpointRouteSpeciesSource
3KM1212J0YUNIIFDA UNII substance identifier--openFDA substances
3KM1212J0YUNIIFDA UNII substance identifier--openFDA substances
3KM1212J0YUNIIFDA UNII substance identifier--openFDA substances
3KM1212J0YUNIIFDA UNII substance identifier--openFDA substances
-%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
2592ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
=5mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID
3unitlessRelative reliability scoreDermalHumanNTP_ICE_skin_sensitization

Showing 8 of 8 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered1,1,2,3,3,6-hexamethylindan-5-yl methyl ketone239-360-0ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Phantolide?

Phantolide has 8 NOAEL studies in the database. The lowest reported value is 3KM1212J0Y UNII. Source: openFDA substances.

What regulatory lists include Phantolide?

Phantolide appears on 2 regulatory/inventory lists including IFRA Transparency, Europe; Personal care; restricted. Source: EPA CPDat.

Is Phantolide used in cosmetics?

Yes, Phantolide is also indexed as a cosmetic ingredient under the name Tetrahydro-hexamethyl-as-indacen-3-one (Phantolide®). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Phantolide come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Phantolide used outside industrial chemicals?

Phantolide also appears in cosmetics databases.