What is the NOAEL for Cocarboxylase chloride?
Cocarboxylase chloride has 4 NOAEL studies in the database. The lowest reported value is XMK8K8EVIU UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Cocarboxylase chloride
Also known as: Bioxylasi, EINECS 205-836-1, Thiaminediphosphate, Thiaminepyrophosphate, Thiaminpyrophosphate (+14 more)
CAS 154-87-0
Cocarboxylase chloride (CAS 154-87-0) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
25 fields
Name
Cocarboxylase chloride
CAS Number
154-87-0
DTXSID
DTXSID6046262
Molecular Formula
C12H18N4O7P2S.ClH
InChI Key
YXVCLPJQTZXJLH-UHFFFAOYSA-N
Monoisotopic Mass
460.013822
Synonyms
BioxylasiEINECS 205-836-1ThiaminediphosphateThiaminepyrophosphateThiaminpyrophosphateCocarboxylasumB-CarbossilasiCocarvitCoenzyme-BConeurinaCothiamineMagnesiocarbina
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| Europe; supplements | EU | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| XMK8K8EVIU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| XMK8K8EVIU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| XMK8K8EVIU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| XMK8K8EVIU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL2104121
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Cocarboxylase chloride?
Cocarboxylase chloride appears on 1 regulatory/inventory list including Europe; supplements. Source: EPA CPDat.
Is Cocarboxylase chloride used in cosmetics?
Yes, Cocarboxylase chloride is also indexed as a cosmetic ingredient under the name Thiamine Diphosphate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Cocarboxylase chloride come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Cocarboxylase chloride used outside industrial chemicals?
Cocarboxylase chloride also appears in cosmetics, pharmaceutical, food safety, cannabis databases.