Thiamine Diphosphate

INCI: THIAMINE DIPHOSPHATE

CAS Number
154-87-0
Function
Skin conditioning
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted for cosmetic use; also used as a dietary supplement ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

None significant; phosphorylated form limits bioavailability through skin

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Concern Level: None

Frequently Asked Questions

Is Thiamine Diphosphate safe in cosmetics?

None significant; phosphorylated form limits bioavailability through skin The EU classifies Thiamine Diphosphate as "permitted". Safety rating: EXCELLENT.

Is Thiamine Diphosphate allowed in the EU?

Thiamine Diphosphate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Thiamine Diphosphate do in cosmetics?

Thiamine Diphosphate functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 154-87-0.

What is the Margin of Safety for Thiamine Diphosphate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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