NOAEL Data REACH Registered Cosmetic Ingredient

Iscotrizinol

Also known as: Bis(2-ethylhexyl) 4,4'-({6-[4-(tert-butylcarbamoyl)anilino]-1,3,5-triazine-2,4-diyl}diazanediyl)dibenzoate, DIETHYLHEXYL BUTAMIDO TRIAZONE, 2-ethylhexyl 4-[[4-[4-(tert-butylcarbamoyl)anilino]-6-[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate, Uvasorb HEB

CAS 154702-15-5

Iscotrizinol (CAS 154702-15-5) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.

View cosmetic safety profile for Uvasorb HEB (Diethylhexyl Butamido Triazone) →

SOURCE NOAEL studies

NOAEL studies

SOURCE Chemical inventory jurisdictions

Regulatory lists

SOURCE EU CLP Annex VI

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 9 fields

Name

Iscotrizinol

CAS Number

154702-15-5

Molecular Formula

C44H59N7O5

InChI Key

OSCJHTSDLYVCQC-UHFFFAOYSA-N

Monoisotopic Mass

765.457768

Synonyms

Bis(2-ethylhexyl) 4,4'-({6-[4-(tert-butylcarbamoyl)anilino]-1,3,5-triazine-2,4-diyl}diazanediyl)dibenzoateDIETHYLHEXYL BUTAMIDO TRIAZONE2-ethylhexyl 4-[[4-[4-(tert-butylcarbamoyl)anilino]-6-[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoateUvasorb HEB

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 3 records

UV stabilizer

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records

List	Keyword	Source
Canada; pharmaceutical	DrugBank	DrugBank

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 8 of 8 studies

Value	Unit	Endpoint	Route	Species	Source
=7.347	mg/m3	DNEL local	inhalation	Human	ToxValDB GESTIS DNEL
=10.86	mg/m3	DNEL systemic	inhalation	Human	ToxValDB GESTIS DNEL
2UTZ0QC864	UNII	FDA UNII substance identifier	-	-	openFDA substances
>2000	mg/kg bw	LD50	oral	Rat	NTP ICE acute oral
=500	mg/kg bw/day	NOAEL	oral	Rat	ECHA
=831	mg/kg bw/day	NOAEL	oral	Rat	ECHA
=963	mg/kg bw/day	NOAEL	oral	Rat	ECHA
>=1000	mg/kg bw/day	NOAEL	dermal	Rat	ECHA

Showing 8 of 8 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA 1 records

Status	Name	EC Number	Link
Registered	bis(2-ethylhexyl) 4,4’-{6-[4-tert-butylcarbamoyl)anilino]-1,3,5-triazine-2,4-diyldiimino}dibenzoate	421-450-8	ECHA overview →

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE ChEMBL / DailyMed ISCOTRIZINOL

ChEMBL Phase

-1

Adverse Events

Bioactivity

View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for Iscotrizinol?

Iscotrizinol has 8 NOAEL studies in the database. The lowest reported value is 7.347 mg/m3 via inhalation in Human. Source: ToxValDB GESTIS DNEL.

What regulatory lists include Iscotrizinol?

Iscotrizinol appears on 1 regulatory/inventory list including Canada; pharmaceutical. Source: EPA CPDat.

Is Iscotrizinol used in cosmetics?

Yes, Iscotrizinol is also indexed as a cosmetic ingredient under the name Uvasorb HEB (Diethylhexyl Butamido Triazone). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Iscotrizinol come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is Iscotrizinol used outside industrial chemicals?

Iscotrizinol also appears in cosmetics, pharmaceutical databases.