What is the NOAEL for Sodium 2-hydroxyethanesulfonate?
Sodium 2-hydroxyethanesulfonate has 9 NOAEL studies in the database. The lowest reported value is 17.6 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Sodium 2-hydroxyethanesulfonate
Also known as: EINECS 216-343-6, NSC 124283, Sodium beta-hydroxyethanesulfonate, Sodium 2-hydroxyethyl sulfonate, UNII-3R36J71C17
CAS 1562-00-1
Sodium 2-hydroxyethanesulfonate (CAS 1562-00-1) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
9
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
Sodium 2-hydroxyethanesulfonate
CAS Number
1562-00-1
DTXSID
DTXSID7027413
Molecular Formula
C2H6O4S.Na
InChI Key
LADXKQRVAFSPTR-UHFFFAOYSA-M
Synonyms
EINECS 216-343-6NSC 124283Sodium beta-hydroxyethanesulfonateSodium 2-hydroxyethyl sulfonateUNII-3R36J71C17
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
39 records
Anti-static agentSoftener and conditionerCleaning agentNo specific technical functionSurfactant (surface active agent)
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| CEDI | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 9 of 9 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =17.6 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| =35.3 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 3R36J71C17 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3R36J71C17 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3R36J71C17 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3R36J71C17 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >5000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =200 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =426 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 9 of 9 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Sodium 2-hydroxyethanesulphonate | 216-343-6 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Surfactant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL172191
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Sodium 2-hydroxyethanesulfonate?
Sodium 2-hydroxyethanesulfonate appears on 1 regulatory/inventory list including CEDI. Source: EPA CPDat.
Is Sodium 2-hydroxyethanesulfonate used in cosmetics?
Yes, Sodium 2-hydroxyethanesulfonate is also indexed as a cosmetic ingredient under the name Sodium Isethionate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Sodium 2-hydroxyethanesulfonate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Sodium 2-hydroxyethanesulfonate used outside industrial chemicals?
Sodium 2-hydroxyethanesulfonate also appears in cosmetics, pharmaceutical databases.