Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Sodium Isethionate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 200 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
None significant. Negative in Ames test, mouse lymphoma assay, and micronucleus assay. Non-irritating to skin and eyes in animal studies
Frequently Asked Questions
Is Sodium Isethionate safe in cosmetics?
None significant. Negative in Ames test, mouse lymphoma assay, and micronucleus assay. Non-irritating to skin and eyes in animal studies The EU classifies Sodium Isethionate as "permitted". Safety rating: EXCELLENT. 1 toxicological study endpoint(s) are available in our database.
Is Sodium Isethionate allowed in the EU?
Sodium Isethionate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Isethionate do in cosmetics?
Sodium Isethionate functions as: Surfactant precursor; used in bath soaps/detergents (the sodium salt of 2-hydroxyethanesulfonic acid). It is classified as a cosmetic ingredient in our database. CAS number: 1562-00-1.
What is the Margin of Safety for Sodium Isethionate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Sodium Isethionate?
The NOAEL (No Observed Adverse Effect Level) for Sodium Isethionate is 200 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.
Compliance Tools
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Related Ingredients
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