What is the NOAEL for 2-Ethyl-3-methylpyrazine?
2-Ethyl-3-methylpyrazine has 6 NOAEL studies in the database. The lowest reported value is 9GF35MK66U UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2-Ethyl-3-methylpyrazine
Also known as: 2-Methyl-3-ethylpyrazine, 3-Ethyl-2-methylpyrazine, Pyrazine, 2-ethyl-3-methyl-, 2-Ethyl-3-methyl-1,4-pyrazine, 3-Methyl-2-ethylpyrazine (+7 more)
CAS 15707-23-0
2-Ethyl-3-methylpyrazine (CAS 15707-23-0) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
18 fields
Name
2-Ethyl-3-methylpyrazine
CAS Number
15707-23-0
DTXSID
DTXSID4047464
Molecular Formula
C7H10N2
InChI Key
LNIMMWYNSBZESE-UHFFFAOYSA-N
Monoisotopic Mass
122.084398
Synonyms
2-Methyl-3-ethylpyrazine3-Ethyl-2-methylpyrazinePyrazine, 2-ethyl-3-methyl-2-Ethyl-3-methyl-1,4-pyrazine3-Methyl-2-ethylpyrazineEC No.: 239-799-85-23-05-00418BRN 0956775EINECS 239-799-8FEMA No. 3155UNII-9GF35MK66U239-799-8
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| consumer_product | P&G | Proctor & Gamble |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 9GF35MK66U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9GF35MK66U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9GF35MK66U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9GF35MK66U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =600 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 5 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-ethyl-3-methylpyrazine | 239-799-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3187840
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 2-Ethyl-3-methylpyrazine?
2-Ethyl-3-methylpyrazine appears on 4 regulatory/inventory lists including IFRA Transparency, Europe, consumer_product, and 1 more. Source: EPA CPDat.
Is 2-Ethyl-3-methylpyrazine used in cosmetics?
Yes, 2-Ethyl-3-methylpyrazine is also indexed as a cosmetic ingredient under the name 2-Ethyl-3-Methylpyrazine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Ethyl-3-methylpyrazine come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 2-Ethyl-3-methylpyrazine used outside industrial chemicals?
2-Ethyl-3-methylpyrazine also appears in cosmetics, pharmaceutical, cannabis databases.