NOAEL Data REACH Registered Cosmetic Ingredient

Phosphonic acid, [[(phosphonomethyl)imino]bis[2,1-ethanediylnitrilobis(methylene)]]tetrakis-

Also known as: DTPMP, EINECS 239-931-4, UNII-0Q75589TM3

CAS 15827-60-8

Phosphonic acid, [[(phosphonomethyl)imino]bis[2,1-ethanediylnitrilobis(methylene)]]tetrakis- (CAS 15827-60-8) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Diethylenetriamine Pentamethylene Phosphonic Acid →

SOURCE noael studies public
NOAEL studies
10
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 9 fields
Name
Phosphonic acid, [[(phosphonomethyl)imino]bis[2,1-ethanediylnitrilobis(methylene)]]tetrakis-
CAS Number
15827-60-8
DTXSID
DTXSID0027775
Molecular Formula
C9H28N3O15P5
InChI Key
DUYCTCQXNHFCSJ-UHFFFAOYSA-N
Monoisotopic Mass
573.020852
Synonyms
DTPMPEINECS 239-931-4UNII-0Q75589TM3

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 1 records
Chelating agent

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
inert_ingredient; non_food_use; PesticidesEPACPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 10 of 10 studies
ValueUnitEndpointRouteSpeciesSource
=10mg/m3DNEL localinhalationHumanToxValDB_GESTIS_DNEL
=7.27mg/m3DNEL systemicinhalationHumanToxValDB_GESTIS_DNEL
0Q75589TM3UNIIFDA UNII substance identifier--openFDA substances
0Q75589TM3UNIIFDA UNII substance identifier--openFDA substances
0Q75589TM3UNIIFDA UNII substance identifier--openFDA substances
0Q75589TM3UNIIFDA UNII substance identifier--openFDA substances
~294mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID
=312mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID
~882mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID
~936mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID

Showing 10 of 10 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered[[(phosphonomethyl)imino]bis[ethane-2,1-diylnitrilobis(methylene)]]tetrakisphosphonic acid239-931-4ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Phosphonic acid, [[(phosphonomethyl)imino]bis[2,1-ethanediylnitrilobis(methylene)]]tetrakis-?

Phosphonic acid, [[(phosphonomethyl)imino]bis[2,1-ethanediylnitrilobis(methylene)]]tetrakis- has 10 NOAEL studies in the database. The lowest reported value is 7.27 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

What regulatory lists include Phosphonic acid, [[(phosphonomethyl)imino]bis[2,1-ethanediylnitrilobis(methylene)]]tetrakis-?

Phosphonic acid, [[(phosphonomethyl)imino]bis[2,1-ethanediylnitrilobis(methylene)]]tetrakis- appears on 1 regulatory/inventory list including inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.

Is Phosphonic acid, [[(phosphonomethyl)imino]bis[2,1-ethanediylnitrilobis(methylene)]]tetrakis- used in cosmetics?

Yes, Phosphonic acid, [[(phosphonomethyl)imino]bis[2,1-ethanediylnitrilobis(methylene)]]tetrakis- is also indexed as a cosmetic ingredient under the name Diethylenetriamine Pentamethylene Phosphonic Acid. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Phosphonic acid, [[(phosphonomethyl)imino]bis[2,1-ethanediylnitrilobis(methylene)]]tetrakis- come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does Phosphonic acid, [[(phosphonomethyl)imino]bis[2,1-ethanediylnitrilobis(methylene)]]tetrakis- have different safety status in cosmetics vs industrial chemicals?

Phosphonic acid, [[(phosphonomethyl)imino]bis[2,1-ethanediylnitrilobis(methylene)]]tetrakis- is classified GHS Danger (H290, H314, H315, H318) in the chemicals database but is allowed in EU cosmetics.

Is Phosphonic acid, [[(phosphonomethyl)imino]bis[2,1-ethanediylnitrilobis(methylene)]]tetrakis- used outside industrial chemicals?

Phosphonic acid, [[(phosphonomethyl)imino]bis[2,1-ethanediylnitrilobis(methylene)]]tetrakis- also appears in cosmetics databases.