Diethylenetriamine Pentamethylene Phosphonic Acid
INCI: DIETHYLENETRIAMINE PENTAMETHYLENE PHOSPHONIC ACID
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for Diethylenetriamine Pentamethylene Phosphonic Acid. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 82.5 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 82.5 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | >=195 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
May contain residual diethylenetriamine and must be specified; environmental persistence concern due to poor phosphonate biodegradability; well-established use history in detergents and cosmetics
Frequently Asked Questions
Is Diethylenetriamine Pentamethylene Phosphonic Acid safe in cosmetics?
May contain residual diethylenetriamine and must be specified; environmental persistence concern due to poor phosphonate biodegradability; well-established use history in detergents and cosmetics The EU classifies Diethylenetriamine Pentamethylene Phosphonic Acid as "permitted". Safety rating: GOOD. 3 toxicological study endpoint(s) are available in our database.
Is Diethylenetriamine Pentamethylene Phosphonic Acid allowed in the EU?
Diethylenetriamine Pentamethylene Phosphonic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Diethylenetriamine Pentamethylene Phosphonic Acid do in cosmetics?
Diethylenetriamine Pentamethylene Phosphonic Acid functions as: Chelating agent. It is classified as a cosmetic ingredient in our database. CAS number: 15827-60-8.
What is the Margin of Safety for Diethylenetriamine Pentamethylene Phosphonic Acid?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Diethylenetriamine Pentamethylene Phosphonic Acid?
The NOAEL (No Observed Adverse Effect Level) for Diethylenetriamine Pentamethylene Phosphonic Acid is 82.5 mg/kg bw/day based on a oral study via oral route in rat. A total of 3 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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