What is the NOAEL for 4-(tert-Pentyl)-cyclohexanone?
4-(tert-Pentyl)-cyclohexanone has 13 NOAEL studies in the database. The lowest reported value is 0.663218143681608 uM. Source: NTP_ICE_endocrine.
NOAEL Data
REACH Registered
Cosmetic Ingredient
4-(tert-Pentyl)-cyclohexanone
Also known as: Cyclohexanone, 4-(1,1-dimethylpropyl)-, Cyclohexanone, 4-tert-pentyl-, 4-tert-Pentylcyclohexanone, 4-07-00-00096, 4-tert-Amylcyclohexanone (+4 more)
CAS 16587-71-6
4-(tert-Pentyl)-cyclohexanone (CAS 16587-71-6) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
13
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
15 fields
Name
4-(tert-Pentyl)-cyclohexanone
CAS Number
16587-71-6
DTXSID
DTXSID4047127
Molecular Formula
C11H20O
InChI Key
DCSKAMGZSIRJAQ-UHFFFAOYSA-N
Monoisotopic Mass
168.151415
Synonyms
Cyclohexanone, 4-(1,1-dimethylpropyl)-Cyclohexanone, 4-tert-pentyl-4-tert-Pentylcyclohexanone4-07-00-000964-tert-AmylcyclohexanoneBRN 22404754-(1,1-Dimethylpropyl)cyclohexanoneEINECS 240-642-0NSC 21167
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
6 records
DeodorizerFragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 13 of 13 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 2.60978849726935 | uM | AC50 | - | - | NTP_ICE_endocrine |
| 0.663218143681608 | uM | ACC | - | - | NTP_ICE_endocrine |
| =20 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 5380BWU79X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5380BWU79X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5380BWU79X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5380BWU79X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 5184 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =4700 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| 0.0437 | unitless | Model Score | - | - | NTP_ICE_endocrine |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 13 of 13 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 4-tert-pentylcyclohexanone | 240-642-0 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3182470
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include 4-(tert-Pentyl)-cyclohexanone?
4-(tert-Pentyl)-cyclohexanone appears on 2 regulatory/inventory lists including IFRA Transparency, consumer_product. Source: EPA CPDat.
Is 4-(tert-Pentyl)-cyclohexanone used in cosmetics?
Yes, 4-(tert-Pentyl)-cyclohexanone is also indexed as a cosmetic ingredient under the name Isopentylcyclohexanone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 4-(tert-Pentyl)-cyclohexanone come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 4-(tert-Pentyl)-cyclohexanone used outside industrial chemicals?
4-(tert-Pentyl)-cyclohexanone also appears in cosmetics, pharmaceutical databases.