Is Isopentylcyclohexanone safe in cosmetics?
Isopentylcyclohexanone has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Isopentylcyclohexanone
Also known as: Cyclohexanone, 4-(1,1-dimethylpropyl)-, Cyclohexanone, 4-tert-pentyl-, 4-tert-Pentylcyclohexanone, 4-07-00-00096, 4-tert-Amylcyclohexanone (+4 more)
INCI: ISOPENTYLCYCLOHEXANONE
Isopentylcyclohexanone (CAS 16587-71-6) is a cosmetic cosmetic ingredient functioning as Fragrance. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 16587-71-6 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
4-(2-methylbutan-2-yl)cyclohexan-1-one
InChIKey
DCSKAMGZSIRJAQ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no specific CFR restriction; IFRA compliance expected
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Isopentylcyclohexanone.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 5184 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
IFRA Concentration Limits (12 Product Categories)
International Fragrance Association standards per product category. Restriction: Restriction. Effective: 2024-01-01.
| Category | Max % | Category | Max % |
|---|---|---|---|
| 1 (Lip products) | – | 7a (Deodorant – not spray) | – |
| 2 (Body spray) | – | 7b (Deodorant spray) | – |
| 3 (Body cream) | – | 8 (Face cream) | – |
| 4 (Fine fragrance) | – | 9 (Soap) | – |
| 5a (Body lotion) | – | 10a (Household – non-spray) | – |
| 5b (Face cream leave-on) | – | 10b (Household – spray) | – |
| 5c (Hand cream) | – | 11a (Intimate – leave-on) | – |
| 5d (Baby cream) | – | 11b (Intimate – rinse) | – |
| 6 (Mouthwash) | – | 12 (Not for consumer exposure) | – |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Deodorizer
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Isopentylcyclohexanone.
Regulatory Flags
fragrance-component
ifra_fragrance
Known Synonyms
Cyclohexanone, 4-(1,1-dimethylpropyl)-
Cyclohexanone, 4-tert-pentyl-
4-tert-Pentylcyclohexanone
4-07-00-00096
4-tert-Amylcyclohexanone
BRN 2240475
4-(1,1-Dimethylpropyl)cyclohexanone
EINECS 240-642-0
NSC 21167
Chemical Function
Deodorizer
Fragrance
Regulatory Lists
IFRA Transparency
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3182470
Frequently Asked Questions
Is Isopentylcyclohexanone allowed in the EU?
Isopentylcyclohexanone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isopentylcyclohexanone do in cosmetics?
Isopentylcyclohexanone functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 16587-71-6.
Is Isopentylcyclohexanone used outside cosmetics?
Isopentylcyclohexanone also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Isopentylcyclohexanone compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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