What is the NOAEL for Sodium hexafluorosilicate?
Sodium hexafluorosilicate has 6 NOAEL studies in the database. The lowest reported value is 2.5 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Sodium hexafluorosilicate
Also known as: Caswell No. 771, Destruxol applex, Disodium hexafluorosilicate (2-), Disodium silicofluoride, EINECS 240-934-8 (+13 more)
CAS 16893-85-9
Sodium hexafluorosilicate (CAS 16893-85-9) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
Cross-Vertical Regulatory Divergence
Sodium hexafluorosilicate is classified GHS Danger (H301, H311, H331, H402, H412) in the chemicals database but is restricted in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
24 fields
Name
Sodium hexafluorosilicate
CAS Number
16893-85-9
DTXSID
DTXSID9036933
Molecular Formula
F6Si.2Na
InChI Key
TWGUZEUZLCYTCG-UHFFFAOYSA-N
Monoisotopic Mass
187.946884
Synonyms
Caswell No. 771Destruxol applexDisodium hexafluorosilicate (2-)Disodium silicofluorideEINECS 240-934-8Ens-zem weevil baitEPA Pesticide Chemical Code 075306Fluosilicate de sodiumOrtho earwig baitOrtho weevil baitPSC Co-Op weevil baitSalufer
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| GHS Signal Word | DANGER |
| GHS Hazard Statements | Toxic if swallowed May cause damage to blood and cardiovascular system Causes damage to the bones and the teeth through prolonged or repeated exposure |
| Short-term Effects | The substance may cause effects on the blood and calcium metabolism. This may result in cardiac disorders. Medical observation is indicated. See Notes. |
| Long-term Effects | The substance may have effects on the bones and teeth. This may result in fluorosis. |
| Routes of Exposure | The substance can be absorbed into the body by ingestion. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
13 records
AbrasiveAnti-scaling agentPharmaceuticalDegradant/impurity
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
| Europe; Personal care; restricted | European Commission | CosIng |
| active_ingredient; Europe; Pesticides | European Commission | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =2.5 | mg/m3 | DNEL local | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 806AV2E065 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 806AV2E065 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 806AV2E065 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 806AV2E065 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Disodium hexafluorosilicate | 240-934-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Cosmetic Ingredient
Frequently Asked Questions
What regulatory lists include Sodium hexafluorosilicate?
Sodium hexafluorosilicate appears on 3 regulatory/inventory lists including active_ingredient; Europe; Pesticides, Europe; Personal care; restricted, inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.
Is Sodium hexafluorosilicate used in cosmetics?
Yes, Sodium hexafluorosilicate is also indexed as a cosmetic ingredient under the name Sodium Fluorosilicate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Sodium hexafluorosilicate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Sodium hexafluorosilicate have different safety status in cosmetics vs industrial chemicals?
Sodium hexafluorosilicate is classified GHS Danger (H301, H311, H331, H402, H412) in the chemicals database but is restricted in EU cosmetics.
Is Sodium hexafluorosilicate used outside industrial chemicals?
Sodium hexafluorosilicate also appears in cosmetics databases.