Moderate Cosmetic Ingredient GHS Classified

Sodium Fluorosilicate

INCI: SODIUM FLUOROSILICATE

CAS Number
16893-85-9
Function
Antiplaque agent, oral care
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted in OTC oral care products under fluoride monograph; regulated as an active ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Signal Word
DANGER
Pictograms
skull;toxic; cancer;health haz
Hazard Statements
Toxic if swallowed May cause damage to blood and cardiovascular system Causes damage to the bones and the teeth through prolonged or repeated exposure
Short-term Exposure Effects
The substance may cause effects on the blood and calcium metabolism. This may result in cardiac disorders. Medical observation is indicated. See Notes.
Long-term Exposure Effects
The substance may have effects on the bones and teeth. This may result in fluorosis.
Routes of Exposure
The substance can be absorbed into the body by ingestion.

Expert Verdict

Acute toxicity via ingestion โ€” fluoride poisoning risk at high doses; restricted to oral care products only; must comply with fluoride labeling requirements; not for use in leave-on skin products

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Concern Level: High

Regulatory Flags

eu_cosing_listed

Frequently Asked Questions

Is Sodium Fluorosilicate safe in cosmetics?

Acute toxicity via ingestion โ€” fluoride poisoning risk at high doses; restricted to oral care products only; must comply with fluoride labeling requirements; not for use in leave-on skin products The EU classifies Sodium Fluorosilicate as "restricted". Safety rating: MODERATE.

Is Sodium Fluorosilicate allowed in the EU?

Sodium Fluorosilicate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium Fluorosilicate do in cosmetics?

Sodium Fluorosilicate functions as: Antiplaque agent, oral care. It is classified as a cosmetic ingredient in our database. CAS number: 16893-85-9.

What is the Margin of Safety for Sodium Fluorosilicate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Is Sodium Fluorosilicate classified as hazardous under GHS?

Sodium Fluorosilicate carries a GHS signal word of "DANGER". Hazard statements: Toxic if swallowed May cause damage to blood and cardiovascular system Causes damage to the bones and the teeth through prolonged or repeated exposure. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance โ€” at cosmetic use concentrations, hazard thresholds may not be met.

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