What is the NOAEL for Disodium fumarate?
Disodium fumarate has 3 NOAEL studies in the database. The lowest reported value is 0578QTK490 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Disodium fumarate
Also known as: 2-Butenedioic acid (2E)-, sodium salt (1:2), 2-Butenedioic acid (2E)-, disodium salt, 2-Butenedioic acid (E)-, disodium salt, Fumarate de disodium, Dinatriumfumarat (+9 more)
CAS 17013-01-3
Disodium fumarate (CAS 17013-01-3) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
3
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
20 fields
Name
Disodium fumarate
CAS Number
17013-01-3
DTXSID
DTXSID10168802
Molecular Formula
C4H4O4.2Na
InChI Key
MSJMDZAOKORVFC-SEPHDYHBSA-L
Monoisotopic Mass
161.990497
Synonyms
2-Butenedioic acid (2E)-, sodium salt (1:2)2-Butenedioic acid (2E)-, disodium salt2-Butenedioic acid (E)-, disodium saltFumarate de disodiumDinatriumfumaratfumarato de disodioFumaric acid disodium saltFUMARATE, DISODIUMEINECS 241-087-7Fumaran sodnyUNII-0578QTK490E365
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
pH regulating agent
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 3 of 3 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 0578QTK490 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0578QTK490 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0578QTK490 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 3 of 3 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ChEMBL Phase
Not listed
Adverse Events
49
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
E365 — ADI: 6 mg/kg bw
View full food safety profile →Frequently Asked Questions
Is Disodium fumarate used in cosmetics?
Yes, Disodium fumarate is also indexed as a cosmetic ingredient under the name Disodium Fumarate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Disodium fumarate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Disodium fumarate used outside industrial chemicals?
Disodium fumarate also appears in cosmetics, pharmaceutical, food safety databases.