NOAEL Data REACH Registered Cosmetic Ingredient

1,1,1,3,5,5,5-Heptamethyl-3-octyltrisiloxane

Also known as: EINECS 241-881-3, UNII-Q95M2P1KJL

CAS 17955-88-3

1,1,1,3,5,5,5-Heptamethyl-3-octyltrisiloxane (CAS 17955-88-3) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Caprylyl Methicone →

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 8 fields

Name

1,1,1,3,5,5,5-Heptamethyl-3-octyltrisiloxane

CAS Number

17955-88-3

DTXSID

DTXSID6051807

Molecular Formula

C15H38O2Si3

InChI Key

SCRSFLUHMDMRFP-UHFFFAOYSA-N

Monoisotopic Mass

334.21796

Synonyms

EINECS 241-881-3UNII-Q95M2P1KJL

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 7 records

Softener and conditionerHumectant

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 2 records

List	Keyword	Source
Canada; Personal care; Substances in PCP - Canada (4/2014)	Government of Canada	CPCat
inert_ingredient; non_food_use; Pesticides	EPA	CPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies

Value	Unit	Endpoint	Route	Species	Source
Q95M2P1KJL	UNII	FDA UNII substance identifier	-	-	openFDA substances
Q95M2P1KJL	UNII	FDA UNII substance identifier	-	-	openFDA substances
Q95M2P1KJL	UNII	FDA UNII substance identifier	-	-	openFDA substances
Q95M2P1KJL	UNII	FDA UNII substance identifier	-	-	openFDA substances

Showing 4 of 4 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records

Status	Name	EC Number	Link
Registered	1,1,1,3,5,5,5-heptamethyl-3-octyltrisiloxane	241-881-3	ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed_with_terms

Conditions

Specific information requirements: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Frequently Asked Questions

What is the NOAEL for 1,1,1,3,5,5,5-Heptamethyl-3-octyltrisiloxane?

1,1,1,3,5,5,5-Heptamethyl-3-octyltrisiloxane has 4 NOAEL studies in the database. The lowest reported value is Q95M2P1KJL UNII. Source: openFDA substances.

What regulatory lists include 1,1,1,3,5,5,5-Heptamethyl-3-octyltrisiloxane?

1,1,1,3,5,5,5-Heptamethyl-3-octyltrisiloxane appears on 2 regulatory/inventory lists including Canada; Personal care; Substances in PCP - Canada (4/2014), inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.

Is 1,1,1,3,5,5,5-Heptamethyl-3-octyltrisiloxane used in cosmetics?

Yes, 1,1,1,3,5,5,5-Heptamethyl-3-octyltrisiloxane is also indexed as a cosmetic ingredient under the name Caprylyl Methicone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 1,1,1,3,5,5,5-Heptamethyl-3-octyltrisiloxane come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is 1,1,1,3,5,5,5-Heptamethyl-3-octyltrisiloxane used outside industrial chemicals?

1,1,1,3,5,5,5-Heptamethyl-3-octyltrisiloxane also appears in cosmetics databases.