Warning GHS07 NOAEL Data REACH Registered Cosmetic Ingredient

Triethoxy(2-methylpropyl)silane

Also known as: Silane, triethoxy(2-methylpropyl)-, (2-Methylpropyl)triethoxysilane, Silane, triethoxyisobutyl-, Isobutyltriethoxysilane, Dynasylan IBTEO (+6 more)

CAS 17980-47-1

Triethoxy(2-methylpropyl)silane (CAS 17980-47-1) is a chemical substance with GHS signal word Warning; key hazard signal: H315. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Hexadecyl Methicone →

SOURCE noael studies public
NOAEL studies
7
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Warning

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 17 fields
Name
Triethoxy(2-methylpropyl)silane
CAS Number
17980-47-1
DTXSID
DTXSID1044857
Molecular Formula
C10H24O3Si
InChI Key
ALVYUZIFSCKIFP-UHFFFAOYSA-N
Monoisotopic Mass
220.149471
Synonyms
Silane, triethoxy(2-methylpropyl)-(2-Methylpropyl)triethoxysilaneSilane, triethoxyisobutyl-IsobutyltriethoxysilaneDynasylan IBTEODynasylan BSM 100NDynasylan BSM 40NZ 6403TriethoxyisobutylsilaneSicong SP 205Xiameter OFS 6403

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications
Hazard ClassH-StatementsPictogramsSignal
Skin Irrit. 2H315GHS07Warning

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
BinderDispersing agent

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 7 of 7 studies
ValueUnitEndpointRouteSpeciesSource
0YZ0G6Z2XHUNIIFDA UNII substance identifier--openFDA substances
0YZ0G6Z2XHUNIIFDA UNII substance identifier--openFDA substances
0YZ0G6Z2XHUNIIFDA UNII substance identifier--openFDA substances
0YZ0G6Z2XHUNIIFDA UNII substance identifier--openFDA substances
>2000mg/kg bwLD50oralRatNTP_ICE_acute_oral
>5000mg/kg bwLD50oralRatNTP_ICE_acute_oral
>=1000mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID

Showing 7 of 7 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredTriethoxyisobutylsilane402-810-3ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed_with_terms
Conditions
Specific information requirements: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Emollient
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL3186627
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Frequently Asked Questions

What is the GHS hazard classification for Triethoxy(2-methylpropyl)silane?

Triethoxy(2-methylpropyl)silane (CAS 17980-47-1) is classified under EU CLP Annex VI as Skin Irrit. 2 with signal word Warning. Hazard statements: H315. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for Triethoxy(2-methylpropyl)silane?

Triethoxy(2-methylpropyl)silane has 7 NOAEL studies in the database. The lowest reported value is 0YZ0G6Z2XH UNII. Source: openFDA substances.

Is Triethoxy(2-methylpropyl)silane used in cosmetics?

Yes, Triethoxy(2-methylpropyl)silane is also indexed as a cosmetic ingredient under the name Hexadecyl Methicone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Triethoxy(2-methylpropyl)silane come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is Triethoxy(2-methylpropyl)silane used outside industrial chemicals?

Triethoxy(2-methylpropyl)silane also appears in cosmetics, pharmaceutical databases.