What is the NOAEL for Edetate dipotassium anhydrous?
Edetate dipotassium anhydrous has 5 NOAEL studies in the database. The lowest reported value is 1.5 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Edetate dipotassium anhydrous
Also known as: Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, potassium salt (1:2), Dipotassium ethylenediaminetetraacetate, EINECS 217-895-0, (Ethylenedinitrilo)tetraacetate dipotassium salt, UNII-3W5S57M958
CAS 2001-94-7
Edetate dipotassium anhydrous (CAS 2001-94-7) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Edetate dipotassium anhydrous is classified GHS CMR hazard (H302, H315, H317, H319, H332, H335, H373, H412) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
Edetate dipotassium anhydrous
CAS Number
2001-94-7
DTXSID
DTXSID3058612
Molecular Formula
C10H16N2O8.2K
InChI Key
QLBHNVFOQLIYTH-UHFFFAOYSA-L
Monoisotopic Mass
370.018078
Synonyms
Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, potassium salt (1:2)Dipotassium ethylenediaminetetraacetateEINECS 217-895-0(Ethylenedinitrilo)tetraacetate dipotassium saltUNII-3W5S57M958
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Chelating agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| CEDI | FDA | United States Food and Drug Administration (FDA) |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =1.5 | mg/m3 | DNEL local | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 3W5S57M958 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3W5S57M958 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3W5S57M958 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3W5S57M958 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Dipotassium dihydrogen ethylenediaminetetraacetate | 217-895-0 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Preservative
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
EDETATE DIPOTASSIUM ANHYDROUS
ChEMBL Phase
-1
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Edetate dipotassium anhydrous?
Edetate dipotassium anhydrous appears on 2 regulatory/inventory lists including CEDI, Indirect additives food contact (10/2018). Source: EPA CPDat.
Is Edetate dipotassium anhydrous used in cosmetics?
Yes, Edetate dipotassium anhydrous is also indexed as a cosmetic ingredient under the name Dipotassium EDTA. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Edetate dipotassium anhydrous come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Edetate dipotassium anhydrous have different safety status in cosmetics vs industrial chemicals?
Edetate dipotassium anhydrous is classified GHS CMR hazard (H302, H315, H317, H319, H332, H335, H373, H412) in the chemicals database but is allowed in EU cosmetics.
Is Edetate dipotassium anhydrous used outside industrial chemicals?
Edetate dipotassium anhydrous also appears in cosmetics, pharmaceutical databases.