Dipotassium EDTA

INCI: DIPOTASSIUM EDTA

CAS Number
2001-94-7
Function
Chelating agent; preservative booster
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” CIR Final Report confirms safety of EDTA and salts (Int J Toxicol 21(Suppl 2):95-142, 2002); FDA permits calcium disodium EDTA as food additive (21 CFR 172.120)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Not biodegradable โ€” environmental persistence concern (not a human safety issue). At very high concentrations, EDTA can enhance penetration of other ingredients by chelating skin barrier calcium. Standard use levels (โ‰ค0.5%) are well within safe range.

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Concern Level: Low

Regulatory Flags

preservative

Frequently Asked Questions

Is Dipotassium EDTA safe in cosmetics?

Not biodegradable โ€” environmental persistence concern (not a human safety issue). At very high concentrations, EDTA can enhance penetration of other ingredients by chelating skin barrier calcium. Standard use levels (โ‰ค0.5%) are well within safe range. The EU classifies Dipotassium EDTA as "permitted". Safety rating: EXCELLENT.

Is Dipotassium EDTA allowed in the EU?

Dipotassium EDTA EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dipotassium EDTA do in cosmetics?

Dipotassium EDTA functions as: Chelating agent; preservative booster. It is classified as a cosmetic ingredient in our database. CAS number: 2001-94-7.

What is the Margin of Safety for Dipotassium EDTA?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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