What is the NOAEL for Pentyl 2-hydroxybenzoate?
Pentyl 2-hydroxybenzoate has 12 NOAEL studies in the database. The lowest reported value is 3.17 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Pentyl 2-hydroxybenzoate
Also known as: Benzoic acid, 2-hydroxy-, pentyl ester, BRN 2577253, Caswell No. 049AA, EINECS 218-080-2, NSC 403668 (+10 more)
CAS 2050-08-0
Pentyl 2-hydroxybenzoate (CAS 2050-08-0) is a chemical substance. Key regulatory status: REACH registered, 7 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
12
SOURCE
chemical inventory jurisdictions
Regulatory lists
7
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
21 fields
Name
Pentyl 2-hydroxybenzoate
CAS Number
2050-08-0
DTXSID
DTXSID9029227
Molecular Formula
C12H16O3
InChI Key
RANVDUNFZBMTBK-UHFFFAOYSA-N
Monoisotopic Mass
208.109944
Synonyms
Benzoic acid, 2-hydroxy-, pentyl esterBRN 2577253Caswell No. 049AAEINECS 218-080-2NSC 403668NSC 44877NSC 46125Pentyl salicylateAmylester kyseliny salicyloveUNII-VZO9C302082-Hydroxybenzoic acid, pentyl esterN-Amyl salicylate
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
FragranceSoftener and conditionerFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
7 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| consumer_product | P&G | Proctor & Gamble |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| air; Cleaning products and household care - air freshener; detected; emissions; Europe | Danish Environmental Protection Agency | Danish EPA |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 12 of 12 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =3.17 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| VZO9C30208 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| VZO9C30208 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| VZO9C30208 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| VZO9C30208 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 6480 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 6750 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =5 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =5 | mg/kg bw/day | NOAEL | oral: unspecified | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =5 | mg/kg bw/day | NOAEL | oral: unspecified | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 12 of 12 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Pentyl salicylate | 218-080-2 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Other
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Pentyl 2-hydroxybenzoate?
Pentyl 2-hydroxybenzoate appears on 7 regulatory/inventory lists including IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), SCIL (9/2019), and 4 more. Source: EPA CPDat.
Is Pentyl 2-hydroxybenzoate used in cosmetics?
Yes, Pentyl 2-hydroxybenzoate is also indexed as a cosmetic ingredient under the name Amyl Salicylate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Pentyl 2-hydroxybenzoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Pentyl 2-hydroxybenzoate used outside industrial chemicals?
Pentyl 2-hydroxybenzoate also appears in cosmetics, food safety, cannabis databases.