Good Cosmetic Ingredient Sensitization Data

Amyl Salicylate

INCI: AMYL SALICYLATE

CAS Number
2050-08-0
Function
Perfuming, Skin Conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR assessed salicylates as safe when formulated to avoid irritation and sun sensitivity

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Amyl Salicylate based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
fragrance
EU Allergen Listed
yes
Patch Test Positive Rate
0.2%
Cross-reactivity Group
none
Reaction Type
contact-dermatitis
IFRA Restricted

Source: EU 2023/1545; SCCS

Expert Verdict

Amyl Salicylate is a restricted fragrance allergen requiring mandatory labeling at >=0.001% (leave-on) or >=0.01% (rinse-off) per EU Annex III.

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Concern Level: Moderate

Regulatory Flags

EU_RESTRICTED ALLERGEN epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Amyl Salicylate safe in cosmetics?

Amyl Salicylate is a restricted fragrance allergen requiring mandatory labeling at >=0.001% (leave-on) or >=0.01% (rinse-off) per EU Annex III. The EU classifies Amyl Salicylate as "restricted". Safety rating: GOOD.

Is Amyl Salicylate allowed in the EU?

Amyl Salicylate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Amyl Salicylate do in cosmetics?

Amyl Salicylate functions as: Perfuming, Skin Conditioning. It is classified as a Cosmetic Ingredient in our database. CAS number: 2050-08-0.

What is the Margin of Safety for Amyl Salicylate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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