What is the NOAEL for Butyl 4-oxopentanoate?
Butyl 4-oxopentanoate has 8 NOAEL studies in the database. The lowest reported value is OI56208RTB UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Butyl 4-oxopentanoate
Also known as: Butyl levulinate, Pentanoic acid, 4-oxo-, butyl ester, 4-03-00-01563, BRN 1768453, Butyl acetylpropionate (+9 more)
CAS 2052-15-5
Butyl 4-oxopentanoate (CAS 2052-15-5) is a chemical substance. Key regulatory status: REACH registered, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
20 fields
Name
Butyl 4-oxopentanoate
CAS Number
2052-15-5
DTXSID
DTXSID3038800
Molecular Formula
C9H16O3
InChI Key
ISBWNEKJSSLXOD-UHFFFAOYSA-N
Monoisotopic Mass
172.109944
Synonyms
Butyl levulinatePentanoic acid, 4-oxo-, butyl ester4-03-00-01563BRN 1768453Butyl acetylpropionateButyl 4-ketovalerateButyl laevulinaten-Butyl laevulinaten-Butyl levulinateEINECS 218-143-4FEMA No. 22074-Ketopentanoic acid butyl ester
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| OI56208RTB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OI56208RTB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OI56208RTB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OI56208RTB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2700 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| >5000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 8 of 8 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | N-butyl 4-oxopentanoate | 218-143-4 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3188634
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Butyl 4-oxopentanoate?
Butyl 4-oxopentanoate appears on 3 regulatory/inventory lists including Europe, IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.
Is Butyl 4-oxopentanoate used in cosmetics?
Yes, Butyl 4-oxopentanoate is also indexed as a cosmetic ingredient under the name Butyl Laevulinate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Butyl 4-oxopentanoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Butyl 4-oxopentanoate used outside industrial chemicals?
Butyl 4-oxopentanoate also appears in cosmetics, pharmaceutical databases.