What is the NOAEL for 2-Ethylhexyl octadecanoate?
2-Ethylhexyl octadecanoate has 6 NOAEL studies in the database. The lowest reported value is EG3PA2K3K5 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2-Ethylhexyl octadecanoate
Also known as: Isooctyl stearate, EINECS 244-754-0, Wickenol 156, UNII-EG3PA2K3K5, Ethylhexyl stearate (+1 more)
CAS 22047-49-0
2-Ethylhexyl octadecanoate (CAS 22047-49-0) is a chemical substance. Key regulatory status: REACH registered, 8 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
8
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
2-Ethylhexyl octadecanoate
CAS Number
22047-49-0
DTXSID
DTXSID9047178
Molecular Formula
C26H52O2
InChI Key
OPJWPPVYCOPDCM-UHFFFAOYSA-N
Monoisotopic Mass
396.396731
Synonyms
Isooctyl stearateEINECS 244-754-0Wickenol 156UNII-EG3PA2K3K5Ethylhexyl stearateOctadecanoic acid, 2-ethylhexyl ester
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
10 records
Surfactant (surface active agent)Softener and conditionerFragrancePlasticizerLubricating agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
8 records
| List | Keyword | Source |
|---|---|---|
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - general moisturizing - hand/body lotion | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care - liniment | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| consumer_product | P&G | Proctor & Gamble |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| EG3PA2K3K5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| EG3PA2K3K5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| EG3PA2K3K5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| EG3PA2K3K5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-ethylhexyl stearate | 244-754-0 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
emollient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3184927
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include 2-Ethylhexyl octadecanoate?
2-Ethylhexyl octadecanoate appears on 6 regulatory/inventory lists including children; Europe; Personal care, children; Europe; Personal care - general moisturizing - hand/body lotion, Europe; Personal care - liniment, and 3 more. Source: EPA CPDat.
Is 2-Ethylhexyl octadecanoate used in cosmetics?
Yes, 2-Ethylhexyl octadecanoate is also indexed as a cosmetic ingredient under the name Ethylhexyl Stearate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Ethylhexyl octadecanoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 2-Ethylhexyl octadecanoate used outside industrial chemicals?
2-Ethylhexyl octadecanoate also appears in cosmetics, pharmaceutical databases.