NOAEL Data Cosmetic Ingredient

Demethoxycurcumin

Also known as: 1,6-Heptadiene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-, (1E,6E)-, (1E,6E)-1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione, 1,6-Heptadiene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-, (E,E)-, 1,6-Heptadiene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-7-(p-hydroxyphenyl)-, (1E,6E)-1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione (+4 more)

CAS 22608-11-3

Demethoxycurcumin (CAS 22608-11-3) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.

View cosmetic safety profile for Demethoxycurcumin →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 15 fields
Name
Demethoxycurcumin
CAS Number
22608-11-3
DTXSID
DTXSID00873751
Molecular Formula
C20H18O5
InChI Key
HJTVQHVGMGKONQ-LUZURFALSA-N
Monoisotopic Mass
338.115424
Synonyms
1,6-Heptadiene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-, (1E,6E)-(1E,6E)-1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione1,6-Heptadiene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-, (E,E)-1,6-Heptadiene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-7-(p-hydroxyphenyl)-(1E,6E)-1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione(1E,6E)-1-(4-Hydroxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dioneCurcumin IIDesmethoxycurcuminMonodemethoxycurcumin

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 1 records
Antioxidant

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
W2F8059T80UNIIFDA UNII substance identifier--openFDA substances
W2F8059T80UNIIFDA UNII substance identifier--openFDA substances
W2F8059T80UNIIFDA UNII substance identifier--openFDA substances
W2F8059T80UNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL105360
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
3
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for Demethoxycurcumin?

Demethoxycurcumin has 4 NOAEL studies in the database. The lowest reported value is W2F8059T80 UNII. Source: openFDA substances.

Is Demethoxycurcumin used in cosmetics?

Yes, Demethoxycurcumin is also indexed as a cosmetic ingredient under the name Demethoxycurcumin. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Demethoxycurcumin come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is Demethoxycurcumin used outside industrial chemicals?

Demethoxycurcumin also appears in cosmetics, pharmaceutical databases.