Demethoxycurcumin

INCI: DEMETHOXYCURCUMIN

CAS Number
22608-11-3
Function
Antioxidant / skin conditioning agent (curcuminoid)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no CFR restriction; curcuminoids generally recognized in cosmetic formulations

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Curcuminoid with antioxidant and skin conditioning benefits; limited cosmetic-specific toxicological data and margin of safety not formally established; aquatic toxicity concern (H400) requires careful formulation consideration.

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Concern Level: Moderate

Frequently Asked Questions

Is Demethoxycurcumin safe in cosmetics?

Curcuminoid with antioxidant and skin conditioning benefits; limited cosmetic-specific toxicological data and margin of safety not formally established; aquatic toxicity concern (H400) requires careful formulation consideration. The EU classifies Demethoxycurcumin as "permitted". Safety rating: GOOD.

Is Demethoxycurcumin allowed in the EU?

Demethoxycurcumin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Demethoxycurcumin do in cosmetics?

Demethoxycurcumin functions as: Antioxidant / skin conditioning agent (curcuminoid). It is classified as a cosmetic ingredient in our database. CAS number: 22608-11-3.

What is the Margin of Safety for Demethoxycurcumin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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