NOAEL Data REACH Registered Cosmetic Ingredient

Stearoxypropyltrimonium chloride

Also known as: UNII-LC1M3R2X4H, 1-Propanaminium, N,N,N-trimethyl-3-(octadecyloxy)-, chloride, 1-Propanaminium, N,N,N-trimethyl-3-(octadecyloxy)-, chloride (1:1), 3-Octadecyloxypropyltrimethylammonium chloride, Ammonium, trimethyl(3-(octadecyloxy)propyl)-, chloride (+1 more)

CAS 23328-71-4

Stearoxypropyltrimonium chloride (CAS 23328-71-4) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Stearoxypropyltrimonium Chloride →

SOURCE noael studies public
NOAEL studies
7
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 12 fields
Name
Stearoxypropyltrimonium chloride
CAS Number
23328-71-4
DTXSID
DTXSID10177878
Molecular Formula
C24H52NO.ClH
InChI Key
QMGAJHYFGBHHRR-UHFFFAOYSA-M
Monoisotopic Mass
406.381568
Synonyms
UNII-LC1M3R2X4H1-Propanaminium, N,N,N-trimethyl-3-(octadecyloxy)-, chloride1-Propanaminium, N,N,N-trimethyl-3-(octadecyloxy)-, chloride (1:1)3-Octadecyloxypropyltrimethylammonium chlorideAmmonium, trimethyl(3-(octadecyloxy)propyl)-, chlorideQuartamin E-80k

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 3 records
Surfactant (surface active agent)Cleaning agentSoftener and conditioner

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 7 of 7 studies
ValueUnitEndpointRouteSpeciesSource
LC1M3R2X4HUNIIFDA UNII substance identifier--openFDA substances
LC1M3R2X4HUNIIFDA UNII substance identifier--openFDA substances
LC1M3R2X4HUNIIFDA UNII substance identifier--openFDA substances
LC1M3R2X4HUNIIFDA UNII substance identifier--openFDA substances
=5mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID
=2mg/kg bw/dayNOELoralRatToxValDB_ECHA_IUCLID
=25mg/kg bw/dayNOELoralRatToxValDB_ECHA_IUCLID

Showing 7 of 7 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredN,N,N-trimethyl-3-(octadecyloxy)propan-1-ammonium chloride700-414-8ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed_with_terms
Conditions
Specific information requirements: Obligations to provide information apply. These obligations are: 1. A person introducing this chemical must tell us in writing within 28 calendar days if any of the following circumstances have occurred in relation to their introduction (importation or manufacture): a. the concentration of the chemical in hair conditioner products exceeds 6% 2. A person who introduces this chemical must tell us in writing within 28 calendar days if they become aware of any of the following circumstances, namely, that since the assessment under the Industrial Chemicals (Notification and Assessment) Act 1989: a. the function or use of the chemical has changed, or is likely to change, significantly; b. the amount of the chemical being introduced has increased, or is likely to increase, significantly; c. in the case of a chemical not manufactured, or proposed to be manufactured, in Australia at the time of the assessment—it has begun to be manufactured in Australia; d. the method of manufacture of the chemical in Australia has changed, or is likely to change, in a way that may result in an increased risk of an adverse effect of the chemical on occupational health and safety, public health or the environment; e. additional information has become available to the person as to an adverse effect of the chemical on occupational health and safety, public health or the environment.

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Hair Conditioning
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Stearoxypropyltrimonium chloride?

Stearoxypropyltrimonium chloride has 7 NOAEL studies in the database. The lowest reported value is LC1M3R2X4H UNII. Source: openFDA substances.

Is Stearoxypropyltrimonium chloride used in cosmetics?

Yes, Stearoxypropyltrimonium chloride is also indexed as a cosmetic ingredient under the name Stearoxypropyltrimonium Chloride. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Stearoxypropyltrimonium chloride come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does Stearoxypropyltrimonium chloride have different safety status in cosmetics vs industrial chemicals?

Stearoxypropyltrimonium chloride is classified GHS Danger (H302, H318, H400, H410) in the chemicals database but is allowed in EU cosmetics.

Is Stearoxypropyltrimonium chloride used outside industrial chemicals?

Stearoxypropyltrimonium chloride also appears in cosmetics databases.