Also known as: C.I. Solvent Blue 18, Acetate Blue G, Acetate Blue 6, Acetoquinone Blue R, Acetylon Fast Blue G (+15 more)
CAS 2475-45-8
C.I. Disperse Blue 1 (CAS 2475-45-8) is a chemical substance with GHS signal word Danger; key hazard signal: H350; H315; H318; H317. Key regulatory status: California Proposition 65, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, IARC, CA Prop 65.
C.I. Disperse Blue 1 is prohibited in EU cosmetics but has active industrial GHS classifications (H350, H315, H318, H317).
CAS, identifiers, formula, and alternate names for the matched substance record.
Carcinogenic hazard classification from IARC monograph evaluations.
| Group | Meaning | Evaluated | Volume |
|---|---|---|---|
| Group 2B | Possibly carcinogenic | 1989 | 48 |
California OEHHA listing status and toxicity category.
| Chemical | Toxicity Type | Cancer | Developmental | Listed |
|---|---|---|---|---|
| - | cancer | Yes | No | - |
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Carc. 1B; Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1 | H350; H315; H318; H317 | GHS08; GHS07; GHS05 | Danger |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| banned; Europe; Personal care | European Commission | CosIng |
| OEHHA Proposition 65 (3/2019) | STATE OF CALIFORNIA ENVIRONMENTAL PROTECTION AGENCY | OEHHA Proposition 65 List |
| OEHHA Proposition 65 (1/2023) | California Office of Environmental Health Hazard Assessment | OEHHA Proposition 65 List |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| AB200 | ug/day | California Proposition 65 NSRL | - | - | California Proposition 65 |
| AB200 | ug/day | California Proposition 65 NSRL | - | - | California Proposition 65 |
| AB200 | ug/day | California Proposition 65 NSRL | - | - | California Proposition 65 |
| AB200 | ug/day | California Proposition 65 NSRL | - | - | California Proposition 65 |
| ABcancer | listing type | California Proposition 65 listing | - | - | California Proposition 65 |
| ABcancer | listing type | California Proposition 65 listing | - | - | California Proposition 65 |
| ABcancer | listing type | California Proposition 65 listing | - | - | California Proposition 65 |
| ABcancer | listing type | California Proposition 65 listing | - | - | California Proposition 65 |
| 2429NAZ8WH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2429NAZ8WH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2429NAZ8WH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2429NAZ8WH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2B | IARC group | IARC carcinogenicity classification | - | - | IARC Monographs |
| 2B | IARC group | IARC carcinogenicity classification | - | - | IARC Monographs |
| 2B | IARC group | IARC carcinogenicity classification | - | - | IARC Monographs |
| 2 | unitless | IARC group | - | - | NTP_ICE_cancer |
| =115.2 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_HESS |
| 2500 | ppm | Top dose | Dosed feed | Mouse | NTP_ICE_cancer |
| 5000 | ppm | Top dose | Dosed feed | Rat | NTP_ICE_cancer |
Showing 19 of 19 studies
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
C.I. Disperse Blue 1 (CAS 2475-45-8) is classified under EU CLP Annex VI as Carc. 1B; Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1 with signal word Danger. Hazard statements: H350; H315; H318; H317. Source: EU CLP Annex VI (ECHA).
C.I. Disperse Blue 1 has 19 NOAEL studies in the database. The lowest reported value is 200 ug/day. Source: California Proposition 65.
C.I. Disperse Blue 1 appears on 3 regulatory/inventory lists including banned; Europe; Personal care, OEHHA Proposition 65 (3/2019), OEHHA Proposition 65 (1/2023). Source: EPA CPDat.
C.I. Disperse Blue 1 is classified by IARC as Group 2B — possibly carcinogenic to humans (evaluated 1989). Source: IARC Monographs on the Identification of Carcinogenic Hazards to Humans.
Yes, C.I. Disperse Blue 1 is listed under California Proposition 65 for cancer. Source: California OEHHA Proposition 65.
Yes, C.I. Disperse Blue 1 is also indexed as a cosmetic ingredient under the name Disperse Blue 1. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, IARC Monographs, California Proposition 65, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
C.I. Disperse Blue 1 is prohibited in EU cosmetics but has active industrial GHS classifications (H350, H315, H318, H317).
C.I. Disperse Blue 1 also appears in cosmetics, pharmaceutical databases.