What is the NOAEL for 2-Phenylethyl 2-methylbutanoate?
2-Phenylethyl 2-methylbutanoate has 7 NOAEL studies in the database. The lowest reported value is 4D2I5SJ45Q UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
2-Phenylethyl 2-methylbutanoate
Also known as: FEMA 3632, Butanoic acid, 2-methyl-, 2-phenylethyl ester, Benzylcarbinyl 2-methylbutyrate, BRN 2266397, Butyric acid, 2-methyl-, phenethyl ester (+6 more)
CAS 24817-51-4
2-Phenylethyl 2-methylbutanoate (CAS 24817-51-4) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Phenethyl 2-Methylbutyrate →
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
17 fields
Name
2-Phenylethyl 2-methylbutanoate
CAS Number
24817-51-4
DTXSID
DTXSID2047567
Molecular Formula
C13H18O2
InChI Key
KVKKTLBBYFABAZ-UHFFFAOYSA-N
Monoisotopic Mass
206.13068
Synonyms
FEMA 3632Butanoic acid, 2-methyl-, 2-phenylethyl esterBenzylcarbinyl 2-methylbutyrateBRN 2266397Butyric acid, 2-methyl-, phenethyl esterEINECS 246-476-5FEMA No. 3632beta-Phenethyl alpha-methylbutanoatebeta-Phenylethyl alpha-methylbutanoatePhenylethyl 2-methylbutyrateUNII-4D2I5SJ45Q
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 4D2I5SJ45Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4D2I5SJ45Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4D2I5SJ45Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4D2I5SJ45Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2700 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 7 of 7 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3183389
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 2-Phenylethyl 2-methylbutanoate?
2-Phenylethyl 2-methylbutanoate appears on 4 regulatory/inventory lists including Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), IFRA Transparency, and 1 more. Source: EPA CPDat.
Is 2-Phenylethyl 2-methylbutanoate used in cosmetics?
Yes, 2-Phenylethyl 2-methylbutanoate is also indexed as a cosmetic ingredient under the name Phenethyl 2-Methylbutyrate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Phenylethyl 2-methylbutanoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 2-Phenylethyl 2-methylbutanoate used outside industrial chemicals?
2-Phenylethyl 2-methylbutanoate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.