What is the NOAEL for Isooctyl 2-mercaptoacetate?
Isooctyl 2-mercaptoacetate has 7 NOAEL studies in the database. The lowest reported value is 4 unitless via Ocular in Rabbit. Source: NTP_ICE_eye_irritation.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Isooctyl 2-mercaptoacetate
Also known as: Isooctyl thioglycolate, Isooctyl alcohol, mercaptoacetate, Thioglycolic acid isooctyl ester, Acetic acid, mercapto-, isooctyl ester, Acetic acid, 2-mercapto-, isooctyl ester (+10 more)
CAS 25103-09-7
Isooctyl 2-mercaptoacetate (CAS 25103-09-7) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Isooctyl 2-mercaptoacetate is prohibited in EU cosmetics at max 8% but has active industrial GHS classifications (H302, H317, H319, H400, H410, H412).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
18 fields
Name
Isooctyl 2-mercaptoacetate
CAS Number
25103-09-7
DTXSID
DTXSID1027841
Synonyms
Isooctyl thioglycolateIsooctyl alcohol, mercaptoacetateThioglycolic acid isooctyl esterAcetic acid, mercapto-, isooctyl esterAcetic acid, 2-mercapto-, isooctyl esterMercaptoacetate d'isooctyleisooctyl mercaptoacetateIsooctylmercaptoacetatmercaptoacetato de isooctiloISOOCTYLTHIOGLYCOLATETHIOGLYCOLATE, ISOOCTYLiso-octyl mercaptoacetate
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Hair waving or straighteningViscosity modifier
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 4 | unitless | EPA Classification | Ocular | Rabbit | NTP_ICE_eye_irritation |
| 3404M9ZDTB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3404M9ZDTB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3404M9ZDTB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3404M9ZDTB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =348 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =3.2 | ppm | NOAEL | inhalation | Rat | ToxValDB_ECHA_IUCLID |
Showing 7 of 7 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Isooctyl mercaptoacetate | 246-613-9 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
8%
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL1889775
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Frequently Asked Questions
Is Isooctyl 2-mercaptoacetate used in cosmetics?
Yes, Isooctyl 2-mercaptoacetate is also indexed as a cosmetic ingredient under the name Isooctyl Thioglycolate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Isooctyl 2-mercaptoacetate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Isooctyl 2-mercaptoacetate have different safety status in cosmetics vs industrial chemicals?
Isooctyl 2-mercaptoacetate is prohibited in EU cosmetics at max 8% but has active industrial GHS classifications (H302, H317, H319, H400, H410, H412).
Is Isooctyl 2-mercaptoacetate used outside industrial chemicals?
Isooctyl 2-mercaptoacetate also appears in cosmetics, pharmaceutical databases.