Isooctyl Thioglycolate

INCI: ISOOCTYL THIOGLYCOLATE

CAS Number
25103-09-7
Function
Depilatory / hair-waving reducing agent (thioglycolic acid ester)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
EU Max Conc. 8%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted with labeling requirements โ€” 21 CFR 700.18 requires specific cautionary statements for thioglycolate-containing products

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Strong skin and eye irritant with mandatory pH range of 7โ€“9.5 for general use or up to 12.7 for professional use; keep away from eyes and not for use on children under 16 in professional products.

โš ๏ธ
Concern Level: High

Frequently Asked Questions

Is Isooctyl Thioglycolate safe in cosmetics?

Strong skin and eye irritant with mandatory pH range of 7โ€“9.5 for general use or up to 12.7 for professional use; keep away from eyes and not for use on children under 16 in professional products. The EU classifies Isooctyl Thioglycolate as "prohibited". Safety rating: MODERATE.

Is Isooctyl Thioglycolate allowed in the EU?

Isooctyl Thioglycolate EU regulatory status: prohibited. Maximum allowed concentration: 8%. This is based on EU Regulation 1223/2009 and its amendments.

What does Isooctyl Thioglycolate do in cosmetics?

Isooctyl Thioglycolate functions as: Depilatory / hair-waving reducing agent (thioglycolic acid ester). It is classified as a cosmetic ingredient in our database. CAS number: 25103-09-7.

What is the Margin of Safety for Isooctyl Thioglycolate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Isooctyl Thioglycolate in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Isooctyl Thioglycolate in your formulation.