What is the NOAEL for (E,E)-2,4-Decadienal?
(E,E)-2,4-Decadienal has 6 NOAEL studies in the database. The lowest reported value is 3G88X2RK09 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
(E,E)-2,4-Decadienal
Also known as: (2E,4E)-Deca-2,4-dienal, 4-01-00-03566, BRN 1704897, EINECS 246-668-9, UNII-3G88X2RK09
CAS 25152-84-5
(E,E)-2,4-Decadienal (CAS 25152-84-5) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Trans, Trans-2,4-Decadienal ⚠ →
Cross-Vertical Regulatory Divergence
(E,E)-2,4-Decadienal is prohibited in EU cosmetics but has active industrial GHS classifications (H312, H315, H319, H335).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
(E,E)-2,4-Decadienal
CAS Number
25152-84-5
DTXSID
DTXSID6024911
Molecular Formula
C10H16O
InChI Key
JZQKTMZYLHNFPL-BLHCBFLLSA-N
Monoisotopic Mass
152.120115
Synonyms
(2E,4E)-Deca-2,4-dienal4-01-00-03566BRN 1704897EINECS 246-668-9UNII-3G88X2RK09
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| detected; Toys and children's products | Springer Berlin Heidelberg | Published Articles |
| detected; Toys and children's products | Scientific Reports | Published Articles |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 3G88X2RK09 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3G88X2RK09 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3G88X2RK09 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3G88X2RK09 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 33.9 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| =100 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_HESS |
Showing 6 of 6 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL443949
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
3
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include (E,E)-2,4-Decadienal?
(E,E)-2,4-Decadienal appears on 3 regulatory/inventory lists including detected; Toys and children's products, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Europe. Source: EPA CPDat.
Is (E,E)-2,4-Decadienal used in cosmetics?
Yes, (E,E)-2,4-Decadienal is also indexed as a cosmetic ingredient under the name Trans, Trans-2,4-Decadienal ⚠. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for (E,E)-2,4-Decadienal come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does (E,E)-2,4-Decadienal have different safety status in cosmetics vs industrial chemicals?
(E,E)-2,4-Decadienal is prohibited in EU cosmetics but has active industrial GHS classifications (H312, H315, H319, H335).
Is (E,E)-2,4-Decadienal used outside industrial chemicals?
(E,E)-2,4-Decadienal also appears in cosmetics, pharmaceutical, food safety, cannabis databases.