Is Trans, Trans-2,4-Decadienal ⚠ safe in cosmetics?
Trans, Trans-2,4-Decadienal ⚠ has a safety rating of "POOR" in our database. EU status: prohibited. US status: permitted.
Poor
Cosmetic Ingredient
Trans, Trans-2,4-Decadienal ⚠
Also known as: (2E,4E)-Deca-2,4-dienal, 4-01-00-03566, BRN 1704897, EINECS 246-668-9, UNII-3G88X2RK09
INCI: TRANS, TRANS-2,4-DECADIENAL
Trans, Trans-2,4-Decadienal ⚠ (CAS 25152-84-5) is a cosmetic cosmetic ingredient functioning as Fragrance (fatty, oily, chicken fat odor). NOAEL 100 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 25152-84-5 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Trans, Trans-2,4-Decadienal ⚠ is prohibited in EU cosmetics but has active industrial GHS classifications (H312, H315, H319, H335).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Fragrance (fatty, oily, chicken fat odor)
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
(2E,4E)-deca-2,4-dienal
InChIKey
JZQKTMZYLHNFPL-BLHCBFLLSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
FEMA GRAS 3135 for flavor use only; IFRA prohibited for fragrance
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Trans, Trans-2,4-Decadienal ⚠.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Trans, Trans-2,4-Decadienal ⚠ across SCCS product categories, with measured dermal absorption where available.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
1190
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
2-trans,4-trans-DECADIENAL | 2003 | No safety concern at current levels of intake when used as a flavouring agent | TRS 922-JECFA 61/64 | FAS 52-JECFA 61/235
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (1)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Trans, Trans-2,4-Decadienal ⚠.
Regulatory Flags
fragrance-component
fda_food_additive
Known Synonyms
(2E,4E)-Deca-2,4-dienal
4-01-00-03566
BRN 1704897
EINECS 246-668-9
UNII-3G88X2RK09
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
detected; Toys and children's products
detected; Toys and children's products
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Europe
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL443949
Frequently Asked Questions
Is Trans, Trans-2,4-Decadienal ⚠ allowed in the EU?
Trans, Trans-2,4-Decadienal ⚠ EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Trans, Trans-2,4-Decadienal ⚠ do in cosmetics?
Trans, Trans-2,4-Decadienal ⚠ functions as: Fragrance (fatty, oily, chicken fat odor). It is classified as a cosmetic ingredient in our database. CAS number: 25152-84-5.
Is Trans, Trans-2,4-Decadienal ⚠ used outside cosmetics?
Trans, Trans-2,4-Decadienal ⚠ also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Trans, Trans-2,4-Decadienal ⚠ have different safety status in cosmetics vs industrial chemicals?
Trans, Trans-2,4-Decadienal ⚠ is prohibited in EU cosmetics but has active industrial GHS classifications (H312, H315, H319, H335).
Compliance Tools
Check Trans, Trans-2,4-Decadienal ⚠ compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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