What is the NOAEL for Methylbenzethonium chloride?
Methylbenzethonium chloride has 12 NOAEL studies in the database. The lowest reported value is 4.60751350511395 uM. Source: NTP ICE endocrine.
NOAEL Data
Cosmetic Ingredient
Methylbenzethonium chloride
Also known as: Benzenemethanaminium, N,N-dimethyl-N-(2-(3-(methyl -4-(1,1,3,3-tetramethylbutyl)phenoxy)ethoxy)ethyl) -, chloride (1:1), Ammonium, benzyldimethyl[2-[2-[[4-(1,1,3,3-tetramethylbutyl)tolyl]oxy]ethoxy]ethyl]-, chloride, Benzenemethanaminium, N,N-dimethyl-N-[2-[2-[methyl-4-(1,1,3,3-tetramethylbutyl)phenoxy]ethoxy]ethyl]-, chloride, Benzyldimethyl[2-[2-[[4-(1,1,3,3-tetramethylbutyl)tolyl]oxy]ethoxy]ethyl]ammonium chloride, 2-(2-(p-(Diisobutyl)cresoxy)ethoxy)ethyldimethylbenzylammonium chloride (+14 more)
CAS 25155-18-4
Methylbenzethonium chloride (CAS 25155-18-4) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Methylbenzethonium Chloride →
SOURCE
NOAEL studies
NOAEL studies
12
SOURCE
Chemical inventory jurisdictions
Regulatory lists
2
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
22 fields
Name
Methylbenzethonium chloride
CAS Number
25155-18-4
DTXSID
DTXSID4035708
Synonyms
Benzenemethanaminium, N,N-dimethyl-N-(2-(3-(methyl -4-(1,1,3,3-tetramethylbutyl)phenoxy)ethoxy)ethyl) -, chloride (1:1)Ammonium, benzyldimethyl[2-[2-[[4-(1,1,3,3-tetramethylbutyl)tolyl]oxy]ethoxy]ethyl]-, chlorideBenzenemethanaminium, N,N-dimethyl-N-[2-[2-[methyl-4-(1,1,3,3-tetramethylbutyl)phenoxy]ethoxy]ethyl]-, chlorideBenzyldimethyl[2-[2-[[4-(1,1,3,3-tetramethylbutyl)tolyl]oxy]ethoxy]ethyl]ammonium chloride2-(2-(p-(Diisobutyl)cresoxy)ethoxy)ethyldimethylbenzylammonium chlorideDiaparene chlorideHyamine 10XHyamina 10Benzyldimethyl(2-(2-((4-(1,1,3,3-tetramethylbutyl)tolyl)oxy)ethoxy)ethyl)ammonium chlorideCaswell No. 355Diisobutylcresoxyethoxyethyl dimethyl benzyl ammonium chlorideEINECS 246-675-7
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
Surfactant (surface active agent)BiocideAnti-static agentDeodorizer
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
| pharmaceutical | US International Trade Commission | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 12 of 12 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 7.76094137809895 | uM | AC50 | - | - | NTP ICE endocrine |
| 10.7314350394163 | uM | AC50 | - | - | NTP ICE endocrine |
| 4.60751350511395 | uM | ACC | - | - | NTP ICE endocrine |
| 10.3539056335386 | uM | ACC | - | - | NTP ICE endocrine |
| 4XKK0M5H9M | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4XKK0M5H9M | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4XKK0M5H9M | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4XKK0M5H9M | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0.00154 | unitless | Model Score | - | - | NTP ICE endocrine |
| 0.00822 | unitless | Model Score | - | - | NTP ICE endocrine |
| 0.152 | unitless | Model Score | - | - | NTP ICE endocrine |
| 0.432 | unitless | Model Score | - | - | NTP ICE endocrine |
Showing 12 of 12 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Surfactant
Frequently Asked Questions
What regulatory lists include Methylbenzethonium chloride?
Methylbenzethonium chloride appears on 2 regulatory/inventory lists including Canada; consumer_product; Substances in Products - Canada (4/2014), pharmaceutical. Source: EPA CPDat.
Is Methylbenzethonium chloride used in cosmetics?
Yes, Methylbenzethonium chloride is also indexed as a cosmetic ingredient under the name Methylbenzethonium Chloride. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Methylbenzethonium chloride come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is Methylbenzethonium chloride used outside industrial chemicals?
Methylbenzethonium chloride also appears in cosmetics databases.