Methylbenzethonium Chloride

INCI: METHYLBENZETHONIUM CHLORIDE

CAS Number
25155-18-4
Function
Antimicrobial, antistatic, deodorant, surfactant-cleansing
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not GRAS/GRAE for consumer antiseptic wash products (FDA Final Rule, September 2016). As a cosmetic ingredient (non-drug use), it remains permitted. CIR has reviewed the broader benzethonium chloride family - safe at concentrations up to 0.5% (0.02% for eye-area products)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

H302 (harmful if swallowed), H312 (harmful in contact with skin), H315 (skin irritation); acute oral and dermal toxicity (Category 4). A quaternary ammonium compound; broad-spectrum antimicrobial activity; cationic surfactant properties

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Concern Level: High

Frequently Asked Questions

Is Methylbenzethonium Chloride safe in cosmetics?

H302 (harmful if swallowed), H312 (harmful in contact with skin), H315 (skin irritation); acute oral and dermal toxicity (Category 4). A quaternary ammonium compound; broad-spectrum antimicrobial activity; cationic surfactant properties The EU classifies Methylbenzethonium Chloride as "permitted". Safety rating: MODERATE.

Is Methylbenzethonium Chloride allowed in the EU?

Methylbenzethonium Chloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methylbenzethonium Chloride do in cosmetics?

Methylbenzethonium Chloride functions as: Antimicrobial, antistatic, deodorant, surfactant-cleansing. It is classified as a cosmetic ingredient in our database. CAS number: 25155-18-4.

What is the Margin of Safety for Methylbenzethonium Chloride?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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