What is the NOAEL for 4-Nitro-3-methylphenol?
4-Nitro-3-methylphenol has 6 NOAEL studies in the database. The lowest reported value is 2CC94832EU UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
4-Nitro-3-methylphenol
Also known as: 4-06-00-02075, BRN 1868105, EINECS 219-952-5, 3-Methyl-4-nitrophenol, 4-Nitro-1-hydroxy-3-methylbenzene (+7 more)
CAS 2581-34-2
4-Nitro-3-methylphenol (CAS 2581-34-2) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
Cross-Vertical Regulatory Divergence
4-Nitro-3-methylphenol is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H318, H341, H401, H411, H312, H315, H319).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
18 fields
Name
4-Nitro-3-methylphenol
CAS Number
2581-34-2
DTXSID
DTXSID2062535
Molecular Formula
C7H7NO3
InChI Key
PIIZYNQECPTVEO-UHFFFAOYSA-N
Monoisotopic Mass
153.042593
Synonyms
4-06-00-02075BRN 1868105EINECS 219-952-53-Methyl-4-nitrophenol4-Nitro-1-hydroxy-3-methylbenzene2-Nitro-5-hydroxytoluene4-Nitro-m-cresolNSC 691904-Nitro-3-cresol4-Nitro-5-methylphenol5-Hydroxy-2-nitrotoluenePhenol, 3-methyl-4-nitro-
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| Pesticides; residue | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 2CC94832EU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2CC94832EU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2CC94832EU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2CC94832EU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =1200 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 0.01 | mg/kg bw/day | LOEL | Subcutaneous | Rat | NTP_ICE_endocrine |
Showing 6 of 6 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Colorant
Frequently Asked Questions
What regulatory lists include 4-Nitro-3-methylphenol?
4-Nitro-3-methylphenol appears on 1 regulatory/inventory list including Pesticides; residue. Source: EPA CPDat.
Is 4-Nitro-3-methylphenol used in cosmetics?
Yes, 4-Nitro-3-methylphenol is also indexed as a cosmetic ingredient under the name 3-Nitro-P-Cresol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 4-Nitro-3-methylphenol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does 4-Nitro-3-methylphenol have different safety status in cosmetics vs industrial chemicals?
4-Nitro-3-methylphenol is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H318, H341, H401, H411, H312, H315, H319).
Is 4-Nitro-3-methylphenol used outside industrial chemicals?
4-Nitro-3-methylphenol also appears in cosmetics databases.