Is 3-Nitro-P-Cresol safe in cosmetics?
3-Nitro-P-Cresol has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
Moderate
Cosmetic Ingredient
3-Nitro-P-Cresol
Also known as: 4-06-00-02075, BRN 1868105, EINECS 219-952-5, 3-Methyl-4-nitrophenol, 4-Nitro-1-hydroxy-3-methylbenzene (+7 more)
INCI: 3-NITRO-P-CRESOL
3-Nitro-P-Cresol (CAS 2581-34-2) is a cosmetic cosmetic ingredient functioning as Hair Dye (semi-permanent / non-oxidative). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 2581-34-2 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
3-Nitro-P-Cresol is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H318, H341, H401, H411, H312, H315, H319).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Hair Dye (semi-permanent / non-oxidative)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
3-methyl-4-nitrophenol
InChIKey
PIIZYNQECPTVEO-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
FDA does not pre-approve hair dye ingredients (coal-tar exemption applies); CIR has reviewed amino-cresol hair dyes
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 3-Nitro-P-Cresol.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Expert Verdict
Expert safety assessment and concern-level summary for 3-Nitro-P-Cresol.
Known Synonyms
4-06-00-02075
BRN 1868105
EINECS 219-952-5
3-Methyl-4-nitrophenol
4-Nitro-1-hydroxy-3-methylbenzene
2-Nitro-5-hydroxytoluene
4-Nitro-m-cresol
NSC 69190
4-Nitro-3-cresol
4-Nitro-5-methylphenol
5-Hydroxy-2-nitrotoluene
Phenol, 3-methyl-4-nitro-
Regulatory Lists
Pesticides; residue
Australian Status
AICIS status: listed
Frequently Asked Questions
Is 3-Nitro-P-Cresol allowed in the EU?
3-Nitro-P-Cresol EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does 3-Nitro-P-Cresol do in cosmetics?
3-Nitro-P-Cresol functions as: Hair Dye (semi-permanent / non-oxidative). It is classified as a cosmetic ingredient in our database. CAS number: 2581-34-2.
Is 3-Nitro-P-Cresol used outside cosmetics?
3-Nitro-P-Cresol also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does 3-Nitro-P-Cresol have different safety status in cosmetics vs industrial chemicals?
3-Nitro-P-Cresol is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H318, H341, H401, H411, H312, H315, H319).
Compliance Tools
Check 3-Nitro-P-Cresol compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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