3-Nitro-P-Cresol

INCI: 3-NITRO-P-CRESOL

CAS Number
2581-34-2
Function
Hair Dye (semi-permanent / non-oxidative)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA does not pre-approve hair dye ingredients (coal-tar exemption applies); CIR has reviewed amino-cresol hair dyes

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Nitro-aromatic compound with general concern for potential mutagenicity; must be supported by negative Ames/genotoxicity data. EU has banned certain amino-cresol variants lacking sufficient safety data. Ensure compliance with specific Annex II entry conditions.

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Concern Level: High

Frequently Asked Questions

Is 3-Nitro-P-Cresol safe in cosmetics?

Nitro-aromatic compound with general concern for potential mutagenicity; must be supported by negative Ames/genotoxicity data. EU has banned certain amino-cresol variants lacking sufficient safety data. Ensure compliance with specific Annex II entry conditions. The EU classifies 3-Nitro-P-Cresol as "prohibited". Safety rating: MODERATE.

Is 3-Nitro-P-Cresol allowed in the EU?

3-Nitro-P-Cresol EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does 3-Nitro-P-Cresol do in cosmetics?

3-Nitro-P-Cresol functions as: Hair Dye (semi-permanent / non-oxidative). It is classified as a cosmetic ingredient in our database. CAS number: 2581-34-2.

What is the Margin of Safety for 3-Nitro-P-Cresol?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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