What is the NOAEL for C.I.Direct Red 80?
C.I.Direct Red 80 has 5 NOAEL studies in the database. The lowest reported value is 16.4 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
C.I.Direct Red 80
Also known as: 2-Naphthalenesulfonic acid, 7,7'-(carbonyldiimino)bis[4-hydroxy-3-[[2-sulfo-4-[(4-sulfophenyl)azo]phenyl]azo]-, hexasodium salt, C.I. 35780, 2-Naphthalenesulfonic acid, 7,7'-(carbonyldiimino)bis[4-hydroxy-3-[2-[2-sulfo-4-[2-(4-sulfophenyl)diazenyl]phenyl]diazenyl]-, sodium salt (1:6), 2-Naphthalenesulfonic acid, 7,7'-(carbonyldiimino)bis(4-hydroxy-3-((2-sulfo-4-((4-sulfophenyl)azo)phenyl)azo)-, hexasodium salt, Hexasodium 7,7'-(carbonyldiimino)bis(4-hydroxy-3-((2-sulphonato-4-((4-sulphonatophenyl)azo)phenyl)azo)naphthalene-2-sulphonate) (+15 more)
CAS 2610-10-8
C.I.Direct Red 80 (CAS 2610-10-8) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
C.I.Direct Red 80 is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H319, H411, H412).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
C.I.Direct Red 80
CAS Number
2610-10-8
DTXSID
DTXSID8044628
Molecular Formula
C45H32N10O21S6.6Na
InChI Key
YIQKLZYTHXTDDT-UHFFFAOYSA-H
Monoisotopic Mass
1377.945391
Synonyms
2-Naphthalenesulfonic acid, 7,7'-(carbonyldiimino)bis[4-hydroxy-3-[[2-sulfo-4-[(4-sulfophenyl)azo]phenyl]azo]-, hexasodium saltC.I. 357802-Naphthalenesulfonic acid, 7,7'-(carbonyldiimino)bis[4-hydroxy-3-[2-[2-sulfo-4-[2-(4-sulfophenyl)diazenyl]phenyl]diazenyl]-, sodium salt (1:6)2-Naphthalenesulfonic acid, 7,7'-(carbonyldiimino)bis(4-hydroxy-3-((2-sulfo-4-((4-sulfophenyl)azo)phenyl)azo)-, hexasodium saltHexasodium 7,7'-(carbonyldiimino)bis(4-hydroxy-3-((2-sulphonato-4-((4-sulphonatophenyl)azo)phenyl)azo)naphthalene-2-sulphonate)EINECS 220-027-3C.I. Direct Red 80, hexasodium saltAhco Direct Fast Red 8BLNAmanil Fast Red 8BLNBelamine Fast Red 8BLNBenzanil Fast Brilliant Red BCalcomine Fast Red 8B
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Dye
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| banned; Europe; Personal care | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =16.4 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 1294D5G72N | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1294D5G72N | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1294D5G72N | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1294D5G72N | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Hexasodium 7,7'-(carbonyldiimino)bis[4-hydroxy-3-[[2-sulphonato-4-[(4-sulphonatophenyl)azo]phenyl]azo]naphthalene-2-sulphonate] | 220-027-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Colorant
Frequently Asked Questions
What regulatory lists include C.I.Direct Red 80?
C.I.Direct Red 80 appears on 1 regulatory/inventory list including banned; Europe; Personal care. Source: EPA CPDat.
Is C.I.Direct Red 80 used in cosmetics?
Yes, C.I.Direct Red 80 is also indexed as a cosmetic ingredient under the name Direct Red 80. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for C.I.Direct Red 80 come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does C.I.Direct Red 80 have different safety status in cosmetics vs industrial chemicals?
C.I.Direct Red 80 is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H319, H411, H412).
Is C.I.Direct Red 80 used outside industrial chemicals?
C.I.Direct Red 80 also appears in cosmetics databases.