Is Direct Red 80 safe in cosmetics?
Direct Red 80 has a safety rating of "POOR" in our database. EU status: prohibited. US status: prohibited.
POOR
Cosmetic Ingredient
Direct Red 80
Also known as: 2-Naphthalenesulfonic acid, 7,7'-(carbonyldiimino)bis[4-hydroxy-3-[[2-sulfo-4-[(4-sulfophenyl)azo]phenyl]azo]-, hexasodium salt, C.I. 35780, 2-Naphthalenesulfonic acid, 7,7'-(carbonyldiimino)bis[4-hydroxy-3-[2-[2-sulfo-4-[2-(4-sulfophenyl)diazenyl]phenyl]diazenyl]-, sodium salt (1:6), 2-Naphthalenesulfonic acid, 7,7'-(carbonyldiimino)bis(4-hydroxy-3-((2-sulfo-4-((4-sulfophenyl)azo)phenyl)azo)-, hexasodium salt, Hexasodium 7,7'-(carbonyldiimino)bis(4-hydroxy-3-((2-sulphonato-4-((4-sulphonatophenyl)azo)phenyl)azo)naphthalene-2-sulphonate) (+15 more)
INCI: DIRECT RED 80
Direct Red 80 (CAS 2610-10-8) is a cosmetic cosmetic ingredient functioning as Colorant. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
Cross-Vertical Regulatory Divergence
Direct Red 80 is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H319, H411, H412).
Source: Cosmetics: ingredients.eu status; Chemicals: ghs classifications.signal word/hazard statement code
Function
Colorant
Editorial assessment
POOR
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
hexasodium;4-hydroxy-7-[[5-hydroxy-7-sulfonato-6-[[2-sulfonato-4-[(4-sulfonatophenyl)diazenyl]phenyl]diazenyl]naphthalen-2-yl]carbamoylamino]-3-[[2-sulfonato-4-[(4-sulfonatophenyl)diazenyl]phenyl]diazenyl]naphthalene-2-sulfonate
InChIKey
YIQKLZYTHXTDDT-UHFFFAOYSA-H
Regulatory Status
EU EU Status
prohibited
US US Status
prohibited
US Notes
Prohibited — not FDA-approved for cosmetic use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Direct Red 80.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Regulatory List Membership (2)
EU Banned in Cosmetics
EU CosIng Cosmetics Ingredient Database
Editorial summary
Preliminary editorial summary for Direct Red 80 — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
colorant
eu_banned_cosmetics
eu_cosing_listed
Known Synonyms
2-Naphthalenesulfonic acid, 7,7'-(carbonyldiimino)bis[4-hydroxy-3-[[2-sulfo-4-[(4-sulfophenyl)azo]phenyl]azo]-, hexasodium salt
C.I. 35780
2-Naphthalenesulfonic acid, 7,7'-(carbonyldiimino)bis[4-hydroxy-3-[2-[2-sulfo-4-[2-(4-sulfophenyl)diazenyl]phenyl]diazenyl]-, sodium salt (1:6)
2-Naphthalenesulfonic acid, 7,7'-(carbonyldiimino)bis(4-hydroxy-3-((2-sulfo-4-((4-sulfophenyl)azo)phenyl)azo)-, hexasodium salt
Hexasodium 7,7'-(carbonyldiimino)bis(4-hydroxy-3-((2-sulphonato-4-((4-sulphonatophenyl)azo)phenyl)azo)naphthalene-2-sulphonate)
EINECS 220-027-3
C.I. Direct Red 80, hexasodium salt
Ahco Direct Fast Red 8BLN
Amanil Fast Red 8BLN
Belamine Fast Red 8BLN
Benzanil Fast Brilliant Red B
Calcomine Fast Red 8B
Chlorantine Fast Red 5BRL
Chlorantine Fast Red 7BLN
Chrome Leather Red 5BRL
Covalene Brilliant Red B
Dermafix Brilliant Red BA
Dialuminous Red F 3B
Diazol Light Red 3B
Dicorel Red L 3A
Chemical Function
Dye
Regulatory Lists
banned; Europe; Personal care
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Direct Red 80 allowed in the EU?
Direct Red 80 EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Direct Red 80 do in cosmetics?
Direct Red 80 functions as: Colorant. It is classified as a cosmetic ingredient in our database. CAS number: 2610-10-8.
Is Direct Red 80 used outside cosmetics?
Direct Red 80 also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Direct Red 80 have different safety status in cosmetics vs industrial chemicals?
Direct Red 80 is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H319, H411, H412).
Compliance Tools
Check Direct Red 80 compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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Direct Red 81
POOR
Chemical family
Colorant
DISODIUM GLUCARATE/GLUCONATE/GLUCURONATE/GLYCOLATE/KETOGLUCONATE/OXALATE/TARTRATE/TARTRONATE
GOOD
Browse nearby
Chelating
DISODIUM SELENITE
MODERATE
Browse nearby
Not Reported
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