What is the NOAEL for 3(2H)-Furanone, 5-ethyl-4-hydroxy-2-methyl-?
3(2H)-Furanone, 5-ethyl-4-hydroxy-2-methyl- has 6 NOAEL studies in the database. The lowest reported value is PG3201707P UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
3(2H)-Furanone, 5-ethyl-4-hydroxy-2-methyl-
CAS 27538-09-6
3(2H)-Furanone, 5-ethyl-4-hydroxy-2-methyl- (CAS 27538-09-6) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for 5-Ethyl-4-Hydroxy-2-Methylfuran-3(2H)-One →
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
6 fields
Name
3(2H)-Furanone, 5-ethyl-4-hydroxy-2-methyl-
CAS Number
27538-09-6
DTXSID
DTXSID80885392
Molecular Formula
C7H10O3
InChI Key
QJYOEDXNPLUUAR-UHFFFAOYSA-N
Monoisotopic Mass
142.062994
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
45 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| PG3201707P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| PG3201707P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| PG3201707P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| PG3201707P | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =200 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =200 | mg/kg bw/day | NOAEL | - | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
Showing 6 of 6 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 3(2H)-Furanone, 5-ethyl-4-hydroxy-2-methyl-?
3(2H)-Furanone, 5-ethyl-4-hydroxy-2-methyl- appears on 3 regulatory/inventory lists including IFRA Transparency, Europe, consumer_product. Source: EPA CPDat.
Is 3(2H)-Furanone, 5-ethyl-4-hydroxy-2-methyl- used in cosmetics?
Yes, 3(2H)-Furanone, 5-ethyl-4-hydroxy-2-methyl- is also indexed as a cosmetic ingredient under the name 5-Ethyl-4-Hydroxy-2-Methylfuran-3(2H)-One. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3(2H)-Furanone, 5-ethyl-4-hydroxy-2-methyl- come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 3(2H)-Furanone, 5-ethyl-4-hydroxy-2-methyl- used outside industrial chemicals?
3(2H)-Furanone, 5-ethyl-4-hydroxy-2-methyl- also appears in cosmetics, cannabis databases.