What is the NOAEL for 3(2H)-Furanone, 2-ethyl-4-hydroxy-5-methyl-?
3(2H)-Furanone, 2-ethyl-4-hydroxy-5-methyl- has 5 NOAEL studies in the database. The lowest reported value is VRF4YF0C3X UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
3(2H)-Furanone, 2-ethyl-4-hydroxy-5-methyl-
CAS 27538-10-9
3(2H)-Furanone, 2-ethyl-4-hydroxy-5-methyl- (CAS 27538-10-9) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for 2-Ethyl-4-Hydroxy-5-Methylfuran-3(2H)-One →
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
6 fields
Name
3(2H)-Furanone, 2-ethyl-4-hydroxy-5-methyl-
CAS Number
27538-10-9
DTXSID
DTXSID40885393
Molecular Formula
C7H10O3
InChI Key
GWCRPYGYVRXVLI-UHFFFAOYSA-N
Monoisotopic Mass
142.062994
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| VRF4YF0C3X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| VRF4YF0C3X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| VRF4YF0C3X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| VRF4YF0C3X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1.52 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-ethyl-4-hydroxy-5-methylfuran-3(2H)-one | 248-514-6 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Frequently Asked Questions
What regulatory lists include 3(2H)-Furanone, 2-ethyl-4-hydroxy-5-methyl-?
3(2H)-Furanone, 2-ethyl-4-hydroxy-5-methyl- appears on 3 regulatory/inventory lists including food_additive; Substances Added to Food (formerly EAFUS) (2/2019), IFRA Transparency, consumer_product. Source: EPA CPDat.
Is 3(2H)-Furanone, 2-ethyl-4-hydroxy-5-methyl- used in cosmetics?
Yes, 3(2H)-Furanone, 2-ethyl-4-hydroxy-5-methyl- is also indexed as a cosmetic ingredient under the name 2-Ethyl-4-Hydroxy-5-Methylfuran-3(2H)-One. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3(2H)-Furanone, 2-ethyl-4-hydroxy-5-methyl- come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is 3(2H)-Furanone, 2-ethyl-4-hydroxy-5-methyl- used outside industrial chemicals?
3(2H)-Furanone, 2-ethyl-4-hydroxy-5-methyl- also appears in cosmetics databases.