What is the NOAEL for 6-Amino-m-cresol?
6-Amino-m-cresol has 21 NOAEL studies in the database. The lowest reported value is 200 mg/kg bw/d. Source: UnifiedCodex:SCCS_SHADOW:beta.noael_studies.
NOAEL Data
Cosmetic Ingredient
6-Amino-m-cresol
Also known as: EINECS 220-620-7, NSC 322874, UNII-QCG4ES2A26
CAS 2835-98-5
6-Amino-m-cresol (CAS 2835-98-5) is a chemical substance. Key regulatory status: 13 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
21
SOURCE
chemical inventory jurisdictions
Regulatory lists
13
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
9 fields
Name
6-Amino-m-cresol
CAS Number
2835-98-5
DTXSID
DTXSID20182594
Molecular Formula
C7H9NO
InChI Key
HCPJEHJGFKWRFM-UHFFFAOYSA-N
Monoisotopic Mass
123.068414
Synonyms
EINECS 220-620-7NSC 322874UNII-QCG4ES2A26
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Dye
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
13 records
| List | Keyword | Source |
|---|---|---|
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| Europe; Personal care - hair coloring | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Personal care - hair coloring - hair color - professional | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Personal care - hair coloring - hair color - professional | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Personal care - hair coloring | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Personal care - hair coloring - hair color - professional | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Personal care - hair coloring - hair color - professional | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Personal care - hair coloring | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Personal care - hair coloring - hair color - permanent | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Personal care - hair coloring - hair color - professional | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Personal care - hair coloring | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Personal care - hair coloring | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Personal care - hair coloring | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 21 of 21 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 200 | mg/kg bw/d | - | - | - | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| QCG4ES2A26 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| QCG4ES2A26 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| QCG4ES2A26 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| QCG4ES2A26 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =50 | mg/kg bw/d | NOAEL | oral | rat | SCCS_vision_codex |
| =50 | mg/kg bw/d | NOAEL | oral | rat | SCCS_vision_codex |
| =50 | mg/kg bw/d | NOAEL | oral | rat | SCCS_vision_codex |
| =50 | mg/kg bw/d | NOAEL | oral | rat | SCCS_vision_codex |
| =200 | mg/kg bw/d | NOAEL | - | - | SCCS_vision_codex |
| =200 | mg/kg bw/d | NOAEL | - | - | SCCS_vision_codex |
| =200 | mg/kg bw/d | NOAEL | - | - | SCCS_vision_codex |
| =200 | mg/kg bw/d | NOAEL | - | - | SCCS_vision_codex |
| =500 | mg/kg bw/d | NOAEL | - | rat | SCCS_vision_codex |
| =500 | mg/kg bw/d | NOAEL | - | rat | SCCS_vision_codex |
| =500 | mg/kg bw/d | NOAEL | - | rat | SCCS_vision_codex |
| =500 | mg/kg bw/d | NOAEL | - | rat | SCCS_vision_codex |
| 500 | mg/kg bw/d | genotoxicity | - | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| 50 | mg/kg bw/d | repeated dose toxicity | oral | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| 50 | mg/kg bw/d | repeated dose toxicity | oral | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| 200 | mg/kg bw/d | repeated dose toxicity | - | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
Showing 21 of 21 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Colorant
Frequently Asked Questions
What regulatory lists include 6-Amino-m-cresol?
6-Amino-m-cresol appears on 5 regulatory/inventory lists including Canada; Personal care; Substances in PCP - Canada (4/2014), Europe; Personal care - hair coloring, detected; Europe; Personal care - hair coloring - hair color - professional, and 2 more. Source: EPA CPDat.
Is 6-Amino-m-cresol used in cosmetics?
Yes, 6-Amino-m-cresol is also indexed as a cosmetic ingredient under the name 6-Amino-M-Cresol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 6-Amino-m-cresol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is 6-Amino-m-cresol used outside industrial chemicals?
6-Amino-m-cresol also appears in cosmetics databases.