Poor Cosmetic Ingredient SCCS/CIR Reviewed

6-Amino-M-Cresol

INCI: 6-AMINO-M-CRESOL

CAS Number
2835-98-5
Function
Hair colorant (oxidative and non-oxidative/semi-permanent hair dye)
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes CIR originally concluded safe; re-opened the assessment after the EU ban. Current status: Insufficient Data Announcement (IDA) โ€” needs method of manufacture data and in vivo genotoxicity studies

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Safety Opinions

Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).

cir September 28, 2023
Verdict: insufficient data

ata to determine the safety of this ingredient. The Panel concluded that the available data are insufficient to make a determination of safety for 6-Amino-m- Cresol under the intended conditions of use as a hair dye ingredient. INTRODUCTION 6-Amino-m-Cresol, which according to the web-based International

Expert Verdict

Genotoxic potential in parent compound and metabolite; banned in EU with insufficient CIR data. Do not formulate.

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Concern Level: High

Regulatory Flags

colorant

Frequently Asked Questions

Is 6-Amino-M-Cresol safe in cosmetics?

Genotoxic potential in parent compound and metabolite; banned in EU with insufficient CIR data. Do not formulate. The EU classifies 6-Amino-M-Cresol as "prohibited". Safety rating: POOR. This ingredient has been reviewed by cir.

Is 6-Amino-M-Cresol allowed in the EU?

6-Amino-M-Cresol EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does 6-Amino-M-Cresol do in cosmetics?

6-Amino-M-Cresol functions as: Hair colorant (oxidative and non-oxidative/semi-permanent hair dye). It is classified as a cosmetic ingredient in our database. CAS number: 2835-98-5.

What is the Margin of Safety for 6-Amino-M-Cresol?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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