What is the NOAEL for Trimethoxycaprylylsilane?
Trimethoxycaprylylsilane has 6 NOAEL studies in the database. The lowest reported value is 12.3 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Trimethoxycaprylylsilane
CAS 3069-40-7
Trimethoxycaprylylsilane (CAS 3069-40-7) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Trimethoxycaprylylsilane is classified GHS Danger (H315, H331, H332) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
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DSSTox identifiers
6 fields
Name
Trimethoxycaprylylsilane
CAS Number
3069-40-7
DTXSID
DTXSID80863094
Molecular Formula
C11H26O3Si
InChI Key
NMEPHPOFYLLFTK-UHFFFAOYSA-N
Monoisotopic Mass
234.165121
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
11 records
BinderHumectantSurface modifierChemical reaction regulatorAdhesion/cohesion promoterDispersing agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =12.3 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| FZ07E4LW2M | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| FZ07E4LW2M | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| FZ07E4LW2M | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| FZ07E4LW2M | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =600 | mg/kg bw/day | LEL | oral | Rat | ToxValDB_EPA_TSCA_8e |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Trimethoxyoctylsilane | 221-338-7 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
UV Filter
Frequently Asked Questions
What regulatory lists include Trimethoxycaprylylsilane?
Trimethoxycaprylylsilane appears on 1 regulatory/inventory list including Canada; Personal care; Substances in PCP - Canada (4/2014). Source: EPA CPDat.
Is Trimethoxycaprylylsilane used in cosmetics?
Yes, Trimethoxycaprylylsilane is also indexed as a cosmetic ingredient under the name Trimethoxycaprylylsilane. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Trimethoxycaprylylsilane come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Trimethoxycaprylylsilane have different safety status in cosmetics vs industrial chemicals?
Trimethoxycaprylylsilane is classified GHS Danger (H315, H331, H332) in the chemicals database but is allowed in EU cosmetics.
Is Trimethoxycaprylylsilane used outside industrial chemicals?
Trimethoxycaprylylsilane also appears in cosmetics databases.