What is the NOAEL for 2-Methylpent-2-en-1-oic acid?
2-Methylpent-2-en-1-oic acid has 3 NOAEL studies in the database. The lowest reported value is 0 % via Dermal in Human. Source: NTP_ICE_skin_sensitization.
NOAEL Data
Cosmetic Ingredient
2-Methylpent-2-en-1-oic acid
Also known as: 2-Methyl-2-pentenoic acid, 2-Pentenoic acid, 2-methyl-, EINECS 221-552-0, FEMA No. 3195
CAS 3142-72-1
2-Methylpent-2-en-1-oic acid (CAS 3142-72-1) is a chemical substance. Key regulatory status: 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for 2-Methylpent-2-Enoic Acid →
Cross-Vertical Regulatory Divergence
2-Methylpent-2-en-1-oic acid is classified GHS Danger (H314, H318) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
3
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
2-Methylpent-2-en-1-oic acid
CAS Number
3142-72-1
DTXSID
DTXSID0051998
Molecular Formula
C6H10O2
InChI Key
JJYWRQLLQAKNAD-UHFFFAOYSA-N
Monoisotopic Mass
114.06808
Synonyms
2-Methyl-2-pentenoic acid2-Pentenoic acid, 2-methyl-EINECS 221-552-0FEMA No. 3195
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
11 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 3 of 3 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 1350 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 3 of 3 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 2-Methylpent-2-en-1-oic acid?
2-Methylpent-2-en-1-oic acid appears on 4 regulatory/inventory lists including Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), consumer_product, and 1 more. Source: EPA CPDat.
Is 2-Methylpent-2-en-1-oic acid used in cosmetics?
Yes, 2-Methylpent-2-en-1-oic acid is also indexed as a cosmetic ingredient under the name 2-Methylpent-2-Enoic Acid. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Methylpent-2-en-1-oic acid come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does 2-Methylpent-2-en-1-oic acid have different safety status in cosmetics vs industrial chemicals?
2-Methylpent-2-en-1-oic acid is classified GHS Danger (H314, H318) in the chemicals database but is allowed in EU cosmetics.
Is 2-Methylpent-2-en-1-oic acid used outside industrial chemicals?
2-Methylpent-2-en-1-oic acid also appears in cosmetics, food safety, cannabis databases.