NOAEL Data Cosmetic Ingredient

5,8,11,14-Eicosatetraenoic acid, 2,3-dihydroxypropyl ester, (all-Z)-

Also known as: 1-Arachidonyl monoglyceride, Arachidonic acid, monoester with 1,2,3-propanetriol

CAS 35474-99-8

5,8,11,14-Eicosatetraenoic acid, 2,3-dihydroxypropyl ester, (all-Z)- (CAS 35474-99-8) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.

View cosmetic safety profile for Glyceryl Arachidonate →

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 8 fields

Name

5,8,11,14-Eicosatetraenoic acid, 2,3-dihydroxypropyl ester, (all-Z)-

CAS Number

35474-99-8

DTXSID

DTXSID501019093

Molecular Formula

C23H38O4

InChI Key

DCPCOKIYJYGMDN-DOFZRALJSA-N

Monoisotopic Mass

378.27701

Synonyms

1-Arachidonyl monoglycerideArachidonic acid, monoester with 1,2,3-propanetriol

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 5 records

Softener and conditionerEmulsifier

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records

List	Keyword	Source
Canada; Personal care; Substances in PCP - Canada (4/2014)	Government of Canada	CPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies

Value	Unit	Endpoint	Route	Species	Source
6UXX4LRJ92	UNII	FDA UNII substance identifier	-	-	openFDA substances
6UXX4LRJ92	UNII	FDA UNII substance identifier	-	-	openFDA substances
6UXX4LRJ92	UNII	FDA UNII substance identifier	-	-	openFDA substances
6UXX4LRJ92	UNII	FDA UNII substance identifier	-	-	openFDA substances

Showing 4 of 4 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

prohibited

Max

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL354786

ChEMBL Phase

Not listed

Adverse Events

Bioactivity

View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for 5,8,11,14-Eicosatetraenoic acid, 2,3-dihydroxypropyl ester, (all-Z)-?

5,8,11,14-Eicosatetraenoic acid, 2,3-dihydroxypropyl ester, (all-Z)- has 4 NOAEL studies in the database. The lowest reported value is 6UXX4LRJ92 UNII. Source: openFDA substances.

What regulatory lists include 5,8,11,14-Eicosatetraenoic acid, 2,3-dihydroxypropyl ester, (all-Z)-?

5,8,11,14-Eicosatetraenoic acid, 2,3-dihydroxypropyl ester, (all-Z)- appears on 1 regulatory/inventory list including Canada; Personal care; Substances in PCP - Canada (4/2014). Source: EPA CPDat.

Is 5,8,11,14-Eicosatetraenoic acid, 2,3-dihydroxypropyl ester, (all-Z)- used in cosmetics?

Yes, 5,8,11,14-Eicosatetraenoic acid, 2,3-dihydroxypropyl ester, (all-Z)- is also indexed as a cosmetic ingredient under the name Glyceryl Arachidonate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 5,8,11,14-Eicosatetraenoic acid, 2,3-dihydroxypropyl ester, (all-Z)- come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is 5,8,11,14-Eicosatetraenoic acid, 2,3-dihydroxypropyl ester, (all-Z)- used outside industrial chemicals?

5,8,11,14-Eicosatetraenoic acid, 2,3-dihydroxypropyl ester, (all-Z)- also appears in cosmetics, pharmaceutical databases.