Poor Cosmetic Ingredient

Glyceryl Arachidonate

INCI: GLYCERYL ARACHIDONATE

CAS Number
35474-99-8
Function
Emollient, skin conditioning agent
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status permitted
US Notes Permitted — not prohibited under 21 CFR; however, CIR found data insufficient.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CIR Expert Panel concluded data insufficient to support safety. Arachidonic acid metabolizes to pro-inflammatory prostaglandins/leukotrienes. CIR requested dermal absorption data and immune system, carcinogenicity, photosensitization, irritation and sensitization studies.

⚠️
Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Glyceryl Arachidonate safe in cosmetics?

CIR Expert Panel concluded data insufficient to support safety. Arachidonic acid metabolizes to pro-inflammatory prostaglandins/leukotrienes. CIR requested dermal absorption data and immune system, carcinogenicity, photosensitization, irritation and sensitization studies. The EU classifies Glyceryl Arachidonate as "prohibited". Safety rating: POOR.

Is Glyceryl Arachidonate allowed in the EU?

Glyceryl Arachidonate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Glyceryl Arachidonate do in cosmetics?

Glyceryl Arachidonate functions as: Emollient, skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 35474-99-8.

What is the Margin of Safety for Glyceryl Arachidonate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Glyceryl Arachidonate compliance across multiple jurisdictions:

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Ingredient Decoder
Paste a full ingredient list for instant analysis
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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