Glyceryl Arachidonate

Also known as: 1-Arachidonyl monoglyceride, Arachidonic acid, monoester with 1,2,3-propanetriol

INCI: GLYCERYL ARACHIDONATE

Glyceryl Arachidonate (CAS 35474-99-8) is a cosmetic cosmetic ingredient functioning as Emollient, skin conditioning agent. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.

View industrial chemical safety profile for CAS 35474-99-8 →

Auto-generated CPSR Part A draft with source citations
Function
Emollient, skin conditioning agent
Safety Rating
POOR

Chemistry & Identifiers

Formula
C23H38O4
MW
378.5 g/mol
PubChem CID
5282281
IUPAC Name
2,3-dihydroxypropyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
InChIKey
DCPCOKIYJYGMDN-DOFZRALJSA-N

Regulatory Status

EU EU Status prohibited
US US Status permitted
US Notes Permitted — not prohibited under 21 CFR; however, CIR found data insufficient.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Glyceryl Arachidonate.

Calculate MoS for your specific formulation with the MoS Calculator.

Additional Ingredient Properties

1 property record from structured ingredient metadata.

emulsifier
{"ingredient_class": "W/O_emulsifier,co_emulsifier", "chemical_type": "glyceryl_ester", "HLB_value": "3.0", "HLB_required_for_oil_phase": "1-5", "emulsion_type_primary": "W/O", "droplet_size_typical_um": "5-10", "surface_tension_reduction_mN_m": "20-22", "interfacial_tension_reduction": "20-25", "foam_formation": "low", "liquid_crystal_formation": "low", "lamellar_phase": "yes", "hexagonal_phase":…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Emulsifier Softener and conditioner

Expert Verdict

Expert safety assessment and concern-level summary for Glyceryl Arachidonate.

Regulatory Flags

potential-allergen

Known Synonyms

1-Arachidonyl monoglyceride Arachidonic acid, monoester with 1,2,3-propanetriol

Chemical Function

Softener and conditioner Emulsifier

Regulatory Lists

Canada; Personal care; Substances in PCP - Canada (4/2014)

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

ChEMBL ID
CHEMBL354786
View full pharmaceutical profile →

Frequently Asked Questions

Is Glyceryl Arachidonate safe in cosmetics?

Glyceryl Arachidonate has a safety rating of "POOR" in our database. EU status: prohibited. US status: permitted.

Is Glyceryl Arachidonate allowed in the EU?

Glyceryl Arachidonate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Glyceryl Arachidonate do in cosmetics?

Glyceryl Arachidonate functions as: Emollient, skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 35474-99-8.

Is Glyceryl Arachidonate used outside cosmetics?

Glyceryl Arachidonate also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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