NOAEL Data REACH Registered Cosmetic Ingredient

Triethylene glycol bis(3-tert-butyl-4-hydroxy-5-methylphenyl)propionate

Also known as: Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, 1,2-ethanediylbis(oxy-2,1-ethanediyl) ester (TK 12627), Benzenepropanoic acid, 3-(1,1-dimethylethyl)-4-hydroxy-5-methyl-, 1,2-ethanediylbis(oxy-2,1-ethanediyl) ester, (Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(3-(3-(tert-butyl)-4-hydroxy-5-methylphenyl)propanoate), BRN 3579178, EINECS 253-039-2 (+1 more)

CAS 36443-68-2

Triethylene glycol bis(3-tert-butyl-4-hydroxy-5-methylphenyl)propionate (CAS 36443-68-2) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Triisodecyl Trimellitate →

SOURCE noael studies public
NOAEL studies
5
SOURCE chemical inventory jurisdictions
Regulatory lists
3
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 12 fields
Name
Triethylene glycol bis(3-tert-butyl-4-hydroxy-5-methylphenyl)propionate
CAS Number
36443-68-2
DTXSID
DTXSID0044236
Molecular Formula
C34H50O8
InChI Key
QSRJVOOOWGXUDY-UHFFFAOYSA-N
Monoisotopic Mass
586.350569
Synonyms
Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, 1,2-ethanediylbis(oxy-2,1-ethanediyl) ester (TK 12627)Benzenepropanoic acid, 3-(1,1-dimethylethyl)-4-hydroxy-5-methyl-, 1,2-ethanediylbis(oxy-2,1-ethanediyl) ester(Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(3-(3-(tert-butyl)-4-hydroxy-5-methylphenyl)propanoate)BRN 3579178EINECS 253-039-2UNII-R24A2HOY7J

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 23 records
AntioxidantUV stabilizer

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 3 records
ListKeywordSource
Europe; plastic_additiveEuropean Chemicals AgencyEuropean Chemicals Agency (ECHA)
Indirect additives food contact (10/2018)FDAUnited States Food and Drug Administration (FDA)
drinking_water; Europe; manufacturing; plastic_additiveBelgaquaCPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 5 of 5 studies
ValueUnitEndpointRouteSpeciesSource
R24A2HOY7JUNIIFDA UNII substance identifier--openFDA substances
R24A2HOY7JUNIIFDA UNII substance identifier--openFDA substances
R24A2HOY7JUNIIFDA UNII substance identifier--openFDA substances
R24A2HOY7JUNIIFDA UNII substance identifier--openFDA substances
>7000mg/kg bwLD50oralRatNTP_ICE_acute_oral

Showing 5 of 5 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredEthylenebis(oxyethylene) bis[3-(5-tert-butyl-4-hydroxy-m-tolyl)propionate]253-039-2ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Emollient
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL3187604
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for Triethylene glycol bis(3-tert-butyl-4-hydroxy-5-methylphenyl)propionate?

Triethylene glycol bis(3-tert-butyl-4-hydroxy-5-methylphenyl)propionate has 5 NOAEL studies in the database. The lowest reported value is R24A2HOY7J UNII. Source: openFDA substances.

What regulatory lists include Triethylene glycol bis(3-tert-butyl-4-hydroxy-5-methylphenyl)propionate?

Triethylene glycol bis(3-tert-butyl-4-hydroxy-5-methylphenyl)propionate appears on 3 regulatory/inventory lists including Europe; plastic_additive, Indirect additives food contact (10/2018), drinking_water; Europe; manufacturing; plastic_additive. Source: EPA CPDat.

Is Triethylene glycol bis(3-tert-butyl-4-hydroxy-5-methylphenyl)propionate used in cosmetics?

Yes, Triethylene glycol bis(3-tert-butyl-4-hydroxy-5-methylphenyl)propionate is also indexed as a cosmetic ingredient under the name Triisodecyl Trimellitate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Triethylene glycol bis(3-tert-butyl-4-hydroxy-5-methylphenyl)propionate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is Triethylene glycol bis(3-tert-butyl-4-hydroxy-5-methylphenyl)propionate used outside industrial chemicals?

Triethylene glycol bis(3-tert-butyl-4-hydroxy-5-methylphenyl)propionate also appears in cosmetics, pharmaceutical databases.