Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
7 study endpoints found for Triisodecyl Trimellitate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 300 mg/kg bw/day | oral | dog | oral | REACH |
| NOEL | 50 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 150 ppm | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | monkey | oral | REACH |
| NOEL | 9 mg/kg bw/day | oral | dog | oral | REACH |
| NOEL | 2000 ppm | oral | rat | oral | REACH |
| NOEL | 300 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Must be formulated to be non-irritating (CIR condition); no carcinogenicity data available in published literature
Frequently Asked Questions
Is Triisodecyl Trimellitate safe in cosmetics?
Must be formulated to be non-irritating (CIR condition); no carcinogenicity data available in published literature The EU classifies Triisodecyl Trimellitate as "permitted". Safety rating: GOOD. 7 toxicological study endpoint(s) are available in our database.
Is Triisodecyl Trimellitate allowed in the EU?
Triisodecyl Trimellitate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Triisodecyl Trimellitate do in cosmetics?
Triisodecyl Trimellitate functions as: Skin conditioning – emollient, occlusive. It is classified as a cosmetic ingredient in our database. CAS number: 36443-68-2.
What is the Margin of Safety for Triisodecyl Trimellitate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Triisodecyl Trimellitate?
The NOAEL (No Observed Adverse Effect Level) for Triisodecyl Trimellitate is 300 mg/kg bw/day based on a oral study via oral route in dog. A total of 7 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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