What is the NOAEL for 2-Cyclohexen-1-one, 3-methyl-5-propyl-?
2-Cyclohexen-1-one, 3-methyl-5-propyl- has 15 NOAEL studies in the database. The lowest reported value is 1 % via Dermal in Human. Source: NTP_ICE_skin_sensitization.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2-Cyclohexen-1-one, 3-methyl-5-propyl-
CAS 3720-16-9
2-Cyclohexen-1-one, 3-methyl-5-propyl- (CAS 3720-16-9) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for 3-Methyl-5-Propyl-2-Cyclohexenone (Celery Ketone) →
SOURCE
noael studies public
NOAEL studies
15
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
6 fields
Name
2-Cyclohexen-1-one, 3-methyl-5-propyl-
CAS Number
3720-16-9
DTXSID
DTXSID80863256
Molecular Formula
C10H16O
InChI Key
URQMEZRQHLCJKR-UHFFFAOYSA-N
Monoisotopic Mass
152.120115
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 15 of 15 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 1.3 | % | Concentration, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 3.3 | % | Concentration, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 1 | % | Concentration, one positive response | Dermal | Human | NTP_ICE_skin_sensitization |
| 6P422HTI94 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6P422HTI94 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6P422HTI94 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6P422HTI94 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 4.545 | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 11.54 | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2025 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 877.5 | ug/cm2 | Induction dose per skin area, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2227 | ug/cm2 | Induction dose per skin area, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 675 | ug/cm2 | Induction dose per skin area, one positive response | Dermal | Human | NTP_ICE_skin_sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 15 of 15 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 3-methyl-5-propylcyclohex-2-enone | 223-069-0 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 2-Cyclohexen-1-one, 3-methyl-5-propyl-?
2-Cyclohexen-1-one, 3-methyl-5-propyl- appears on 4 regulatory/inventory lists including IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), consumer_product, and 1 more. Source: EPA CPDat.
Is 2-Cyclohexen-1-one, 3-methyl-5-propyl- used in cosmetics?
Yes, 2-Cyclohexen-1-one, 3-methyl-5-propyl- is also indexed as a cosmetic ingredient under the name 3-Methyl-5-Propyl-2-Cyclohexenone (Celery Ketone). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Cyclohexen-1-one, 3-methyl-5-propyl- come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 2-Cyclohexen-1-one, 3-methyl-5-propyl- used outside industrial chemicals?
2-Cyclohexen-1-one, 3-methyl-5-propyl- also appears in cosmetics, cannabis databases.