What is the NOAEL for C.I. Acid Red 1?
C.I. Acid Red 1 has 18 NOAEL studies in the database. The lowest reported value is 0.1 mg/kg via oral in Human. Source: ToxValDB_WHO_JECFA_ADI.
NOAEL Data
REACH Registered
Cosmetic Ingredient
C.I. Acid Red 1
Also known as: 2,7-Naphthalenedisulfonic acid, 5-(acetylamino)-4-hydroxy-3-(phenylazo)-, disodium salt, C.I. 18050, 2,7-Naphthalenedisulfonic acid, 5-(acetylamino)-4-hydroxy-3-(2-phenyldiazenyl)-, sodium salt (1:2), EC No.: 223-098-9, C.I. Acid Red 1, disodium salt (+15 more)
CAS 3734-67-6
C.I. Acid Red 1 (CAS 3734-67-6) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
18
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
C.I. Acid Red 1
CAS Number
3734-67-6
DTXSID
DTXSID9044663
Molecular Formula
C18H15N3O8S2.2Na
InChI Key
WXLFIFHRGFOVCD-UHFFFAOYSA-L
Monoisotopic Mass
511.009595
Synonyms
2,7-Naphthalenedisulfonic acid, 5-(acetylamino)-4-hydroxy-3-(phenylazo)-, disodium saltC.I. 180502,7-Naphthalenedisulfonic acid, 5-(acetylamino)-4-hydroxy-3-(2-phenyldiazenyl)-, sodium salt (1:2)EC No.: 223-098-9C.I. Acid Red 1, disodium saltC.I. Food Red 10Acetyl Red GAcetyl Red JAcetyl Rose 2GLAcid Bright RedAcid Brilliant RedAcid Fast Red 3G
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
7 records
DyeFragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| Europe; Personal care | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 18 of 18 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| <=0.1 | mg/kg | ADI | oral | Human | ToxValDB_WHO_JECFA_ADI |
| ~29 | mg/kg bw/day | BMDL (10) | oral | Rat | ToxValDB_EFSA |
| 3365R6427R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3365R6427R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3365R6427R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3365R6427R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =20 | mg/kg bw/day | LOAEL | oral | Mouse | ToxValDB_ECHA_IUCLID |
| =50 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| =10 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =11.4 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =25 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =100 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =129 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =937.5 | mg/kg bw/day | NOAEL | oral | Mouse | ToxValDB_ECHA_IUCLID |
| =1500 | mg/kg bw/day | NOAEL | oral | Mouse | ToxValDB_ECHA_IUCLID |
| =2000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =3000 | mg/kg bw/day | NOAEL | oral | Mouse | ToxValDB_ECHA_IUCLID |
Showing 18 of 18 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Disodium 5-acetylamino-4-hydroxy-3-(phenylazo)naphthalene-2,7-disulphonate | 223-098-9 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Colorants
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
E128 — ADI: 0-0.1 mg/kg bw mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include C.I. Acid Red 1?
C.I. Acid Red 1 appears on 3 regulatory/inventory lists including IFRA Transparency, inert_ingredient; non_food_use; Pesticides, Europe; Personal care. Source: EPA CPDat.
Is C.I. Acid Red 1 used in cosmetics?
Yes, C.I. Acid Red 1 is also indexed as a cosmetic ingredient under the name CI 18050. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for C.I. Acid Red 1 come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is C.I. Acid Red 1 used outside industrial chemicals?
C.I. Acid Red 1 also appears in cosmetics, food safety, cannabis databases.